缺血性脑白质病变与认知功能障碍的相关性研究
发布时间：2018-10-11 12:13
【摘要】：目的探缺血性脑白质病变与认知障碍的关系,为血管性痴呆的预防、早期诊断和治疗提供理论依据。方法选择138例经颅脑MRI证实的脑白质病变患者,并分为缺血性脑白质病变组和非缺血性脑白质病变组,分别进行简易智能状态检查量表(MMSE)评估比较,并对白质病变进行分级,进行组内及两组患者认知功能严重程度比较。结果缺血性白质病变组认知功能障碍发生率及Ⅱ、Ⅲ段白质病变者的认识功能障碍的严重程度明显高于非缺血性白质病变组;组内比较缺血性白质病变组和非缺血性白质病变组认知功能障碍与白质病变严重分级呈正相关,而二者无明显关系。结论缺血性白质病及其严重程度对认知功能障碍的发生及严重程度有显著影响,而非缺血性白质病则对认知功能障碍影响较小。
[Abstract]:Objective to explore the relationship between ischemic white matter lesions and cognitive impairment, and to provide theoretical basis for the prevention, early diagnosis and treatment of vascular dementia. Methods one hundred and eight patients with cerebral white matter disease confirmed by brain MRI were divided into ischemic and non-ischemic white matter disease groups. (MMSE) was used to evaluate and compare the simple Intelligent State Checklist, and the white matter lesions were classified. To compare the severity of cognitive function between the group and the two groups. Results the incidence of cognitive dysfunction and the severity of cognitive dysfunction in patients with 鈪，
本文编号：2264149
[Abstract]:Objective to explore the relationship between ischemic white matter lesions and cognitive impairment, and to provide theoretical basis for the prevention, early diagnosis and treatment of vascular dementia. Methods one hundred and eight patients with cerebral white matter disease confirmed by brain MRI were divided into ischemic and non-ischemic white matter disease groups. (MMSE) was used to evaluate and compare the simple Intelligent State Checklist, and the white matter lesions were classified. To compare the severity of cognitive function between the group and the two groups. Results the incidence of cognitive dysfunction and the severity of cognitive dysfunction in patients with 鈪，
本文编号：2264149
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