双相心境障碍抑郁发作患病严重程度的影响因素分析

发布时间：2019-03-05 13:12

【摘要】：目的研究影响双相心境障碍疾病抑郁发作期严重程度的危险因素,为该病的有效预防提供理论依据。方法收集2010-2015年某市精神专科医院的双相心境障碍抑郁发作住院466名患者的病例信息,根据汉密尔顿抑郁量表将患者分为轻、中、重度,并选出年龄、性别、居住地、出生季节、遗传史等15个可能危险因素,进行单因素和多因素条件Logistic回归分析。结果 Logistic回归分析筛选出7个影响双相心境障碍疾病抑郁发作严重程度的危险因素,即出生季节(冬季OR=3.091、秋季OR=2.363)、高学历(OR=1.414)、婚姻离异(OR=3.132)、长期居住农村(OR=0.587)、排行老大(OR=1.461)、性格内向(OR=1.705)、家族遗传史(OR=2.101)。结论双相心境障碍抑郁发作严重程度受多种因素的影响。
[Abstract]:Objective to study the risk factors affecting the severity of bipolar mood disorder during the onset of depression, and to provide theoretical basis for the effective prevention of the disease. Methods from 2010 to 2015, 466 inpatients with bipolar mood disorder were collected and divided into mild, moderate, severe, age, sex and residence according to Hamilton Depression scale (Hamilton Depression scale), the patients were divided into three groups: age, sex, residence, age, sex, and residence, according to Hamilton Depression scale, the patients were divided into mild, moderate and severe groups. Fifteen possible risk factors, such as birth season and genetic history, were analyzed by univariate and multivariate conditional Logistic regression. Results by Logistic regression analysis, 7 risk factors affecting the severity of bipolar disorder depression were screened, namely, birth season (winter OR=3.091, autumn OR=2.363), high education level (OR=1.414), marital divorce (OR=3.132), and age of birth season (winter OR=3.091, and autumn OR=2.363), high degree of education (OR=1.414) and marital divorce (OR=3.132). Long-term living in rural areas (OR=0.587), ranking boss (OR=1.461), introverts (OR=1.705), family genetic history (OR=2.101). Conclusion the severity of bipolar mood disorder is influenced by many factors.
【作者单位】：哈尔滨医科大学公共卫生学院;哈尔滨市第一专科医院;哈尔滨市中医医院;
【基金】：哈尔滨市科技创新人才基金课题(2014RFXXJ106)
【分类号】：R749.4

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