有冲动攻击行为的双相情感障碍患者认知功能研究
发布时间：2019-05-21 20:43
【摘要】：目的:探讨伴有冲动攻击行为的双相情感障碍患者其认知功能损害的特征,以及双相情感障碍患者的冲动攻击行为是否会进一步加重认知功能的损害,为认知功能损害的预防和干预提供科学的理论依据。方法:本研究采用横断面研究的方法,将于2015年10月至2016年08月,在新疆维吾尔自治区人民医院临床心理科住院,并愿意接受调查的72例双相情感障碍患者进行研究。量表包括,自编一般情况调查表、轻躁狂症状量表(HCL-32)、汉密尔顿抑郁量表(HAMD)、修订版Barratt冲动量表(BIS-11)、修改版外显行为攻击量表(MOAS)、蒙特利尔认知评价量表(MoCA)、威斯康星卡片分类测验(WCST)及Stroop测验工具对双相情感障碍患者进行调查及评估。将所有患者按照修订版Barratt冲动量表(BIS-11)及修改版外显行为攻击量表(MOAS)评分标准,分为攻击组(MOAS加权总分≥5分,且表中”体力攻击”项≥1分;BIS-11总分≥70分)33例与非攻击组(MOAS加权总分5分且”体力攻击”项=0分;BIS-11总分70分)39例。结果:(1)攻击组与非攻击组的一般情况经比较,差异均无统计学意义(P㧐0.05)。(2)攻击组患者HCL-32得分[18(15,22),P㧐0.05]与非攻击组患者HCL-32得分[19(16,23)]所表现出的轻躁狂状态得分无统计学差异性。(3)攻击组与非攻击组无论在注意力冲动性、运动冲动性还是在无计划冲动性上均具有统计学意义(P㩳0.05),即攻击组较非攻击组在冲动性的三个维度表现都明显。(4)攻击组与非攻击组WCST测验,仅在正确应答数、持续性应答数及非持续性错误数方面无统计学意义(P㧐0.05)。攻击组表现出更明显的执行功能损害。(5)攻击组与非攻击组在Stroop色词测验测评结果上未表现出统计学差异(P㧐0.05)。攻击组与非攻击组在反应抑制能力及抗干扰能力上均无明显差异。(6)攻击组MoCA总分23.00(20.00,25.00),非攻击组MoCA总分26.00(23.00,27.00),显然并不是所有患者都存在认知功能的缺损,相比较攻击组从整体上表现出更明显的认知功能损害。攻击组与非攻击组在视空间与执行功能、注意、抽象能力及定向力等方面均具有统计学差异,(P㩳0.05)。结论:(1)在整体研究中,伴有冲动攻击行为的双相情感障碍患者表现出认知功能的损害;而不伴有冲动攻击行为的双相情感障碍患者在整体上并未表现出认知功能的缺损;(2)从个体来说,无论是否伴有冲动攻击行为,双相情感障碍患者都可能存在认知功能损害。(3)有冲动攻击行为的双相情感障碍患者相较于无冲动攻击行为的患者在执行功能、注意、抽象能力及定向力等方面表现出更明显的认知功能损害。(4)冲动攻击行为可以作为预测双相情感障碍患者认知功能进一步损害的独立因素。
[Abstract]:Objective: to investigate the characteristics of cognitive impairment in patients with biphasic affective disorder with impulsive aggression, and whether impulsive aggressive behavior in patients with biphasic affective disorder will further aggravate the impairment of cognitive function. It provides a scientific theoretical basis for the prevention and intervention of cognitive impairment. Methods: a cross-section study was conducted in 72 patients with biphasic affective disorder from October 2015 to August 2016 in the Department of Clinical Psychology of Xinjiang Uygur Autonomous region people's Hospital. The scale includes self-designed general situation questionnaire, mild mania symptom scale (HCL-32), Hamilton depression scale (HAMD), revised Barratt impulse scale (BIS-11), modified explicit behavioral attack scale (MOAS),. The Montreal Cognitive rating scale (MoCA),) was used to investigate and evaluate the patients with biphasic affective disorder with the Wisconsin Card sorting Test (WCST) and the Stroop Test. According to the revised Barratt impulse scale (BIS-11) and the modified explicit behavioral attack scale (MOAS), all patients were divided into attack group (MOAS weighted total score 鈮，
本文编号：2482389
[Abstract]:Objective: to investigate the characteristics of cognitive impairment in patients with biphasic affective disorder with impulsive aggression, and whether impulsive aggressive behavior in patients with biphasic affective disorder will further aggravate the impairment of cognitive function. It provides a scientific theoretical basis for the prevention and intervention of cognitive impairment. Methods: a cross-section study was conducted in 72 patients with biphasic affective disorder from October 2015 to August 2016 in the Department of Clinical Psychology of Xinjiang Uygur Autonomous region people's Hospital. The scale includes self-designed general situation questionnaire, mild mania symptom scale (HCL-32), Hamilton depression scale (HAMD), revised Barratt impulse scale (BIS-11), modified explicit behavioral attack scale (MOAS),. The Montreal Cognitive rating scale (MoCA),) was used to investigate and evaluate the patients with biphasic affective disorder with the Wisconsin Card sorting Test (WCST) and the Stroop Test. According to the revised Barratt impulse scale (BIS-11) and the modified explicit behavioral attack scale (MOAS), all patients were divided into attack group (MOAS weighted total score 鈮，
本文编号：2482389
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