抑郁性障碍患者的症状特点及其与述情障碍特征的关系
发布时间：2019-05-22 23:13
【摘要】：目的：(1)了解不同性别、来源地、年龄、文化程度抑郁性障碍患者的抑郁症状表现特点。(2)探讨抑郁性障碍患者的症状表现与述情障碍特征的关系。 方法：抑郁组307例,分别来自长沙和怀化地区的四家医院,所有入选病例均具有符合DSM-IV诊断标准中抑郁发作的核心症状。正常对照组351例来自门诊就诊患者家属(或陪护人员)。对抑郁组采用结构式访谈了解其临床症状。对所有研究对象采用流调中心用抑郁量表(CES-D)评估其抑郁症状及抑郁水平,使用多伦多述情障碍量表(TAS-20)中文版测查其述情障碍特征。 结果：(1)抑郁组与正常对照组在CES-D的抑郁情绪、躯体症状、积极情绪及人际关系四个因子的得分和量表总分上存在显著差异,抑郁组的得分均显著高于正常对照组(P0.001)。(2)男性抑郁性障碍患者的抑郁情绪因子分显著低于女性(P0.01)；不同文化程度的抑郁性障碍患者的抑郁情绪因子分、躯体症状因子分以及CES-D总分存在显著差异,文化程度在小学及以下的抑郁性障碍患者的抑郁情绪因子分、躯体症状因子分、CES-D总分明显高于其他文化程度的抑郁性障碍患者(P0.05)；不同年龄、不同来源地的抑郁性障碍患者的抑郁症状无显著差异；(3)抑郁组与正常对照组在TAS-20的情感辨别困难、情感描述困难及外向性思维三个因子的得分和量表总分上存在显著差异,抑郁组的得分均显著高于正常对照组(P0.01)。(4)抑郁性障碍患者的CES-D总分与情感辨别困难因子分、情感描述困难因子分、TAS-20总分均显著相关(P0.05)；抑郁情绪因子分与情感辨别困难因子分、情感描述困难因子分、外向性思维因子分及TAS-20总分均显著相关(相关系数为0.122～0.169,P0.05或P0.01)；躯体症状因子分与情感辨别困难因子分、情感描述困难因子分、外向性思维因子分及TAS-20总分均显著相关(P0.05)；积极情绪因子分与外向性思维因子分显著相关(P0.05)；人际困难因子分与TAS-20总分显著相关(P0.05)。高述情障碍抑郁性障碍患者组的CES-D总分、抑郁情绪及躯体症状因子分均显著高于低述情障碍抑郁性障碍患者组(P0.05)。 结论： (1)抑郁性障碍患者的抑郁严重程度以及抑郁症状表现存在性别和文化程度的差异； (2)抑郁性障碍患者相对健康人群表现出更明显的述情障碍； (3)抑郁性障碍患者的症状表现与其述情障碍有关,高述情障碍的抑郁性障碍患者表现出更严重的抑郁症状,更容易表现出躯体化症状。表8张,参考文献86
[Abstract]:Objective: (1) to understand the characteristics of depressive symptoms in patients with depressive disorder of different sex, origin, age and educational level. (2) to explore the relationship between the symptoms of depressive disorders and the characteristics of alexithymia. Methods: 307 patients in depression group were from four hospitals in Changsha and Huaihua respectively. All the selected patients had the core symptoms of depression according to the diagnostic criteria of DSM-IV. In the normal control group, 351 cases came from the family members (or accompanying personnel) of the outpatients. The clinical symptoms of depression group were investigated by structural interview. The depressive symptoms and depression level were evaluated by flow center depression scale (CES-D), and the characteristics of alexithymia were measured by Toronto alexithymia scale (TAS-20) in Chinese. Results: (1) there were significant differences in the scores of depression, physical symptoms, positive emotion and interpersonal relationship between the depression group and the normal control group, as well as the total score of the scale. The scores of depression in depression group were significantly higher than those in normal control group (P0. 001). (2). The scores of depression factor in male patients with depressive disorder were significantly lower than those in women (P 0.01). There were significant differences in depression factor score, somatic symptom factor score and CES-D total score among patients with depressive disorder with different educational levels. the scores of depression factor in patients with depressive disorder with educational level below primary school were significantly different. The score of somatic symptom factor and the total score of CES-D were significantly higher than those of patients with depressive disorder with other educational levels (P 0.05). There was no significant difference in depressive symptoms among patients with depressive disorder of different ages and different places of origin. (3) there were significant differences in the scores of emotional discrimination difficulty, emotional description difficulty and extroverted thinking between the depression group and the normal control group, and the total score of the scale. The scores of depression group were significantly higher than those of normal control group (P 0.01). (4). The total score of CES-D was significantly correlated with the score of emotion discrimination difficulty factor, emotion description difficulty factor and TAS-20 score of patients with depression disorder (P 0.05). Depression emotion factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroverted thinking factor score and TAS-20 total score (correlation coefficient was 0.122 卤0.169, P 0.05 or P 0.01), and there was a significant correlation between depression emotion factor score and emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score. Somatic symptom factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score (P 0.05). The positive emotion factor score was significantly correlated with the extroversion thinking factor score (P 0.05), and the interpersonal difficulty factor score was significantly correlated with the total score of TAS-20 (P 0.05). The total score of CES-D, depressive mood and somatic symptom factors in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05), and the scores of total score, depression emotion and somatic symptoms in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05). Conclusion: (1) there are gender and educational differences in the severity of depression and depressive symptoms in patients with depressive disorder, (2) patients with depressive disorder show more obvious alexithymia than healthy people, and (2) there are more obvious alexithymia in patients with depressive disorder than in healthy people. (3) the symptoms of patients with depressive disorder were related to alexithymia. Patients with depressive disorder with high alexithymia showed more serious depressive symptoms and were more likely to show somatization symptoms. Table 8, references 86
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R749.4
本文编号：2483361
[Abstract]:Objective: (1) to understand the characteristics of depressive symptoms in patients with depressive disorder of different sex, origin, age and educational level. (2) to explore the relationship between the symptoms of depressive disorders and the characteristics of alexithymia. Methods: 307 patients in depression group were from four hospitals in Changsha and Huaihua respectively. All the selected patients had the core symptoms of depression according to the diagnostic criteria of DSM-IV. In the normal control group, 351 cases came from the family members (or accompanying personnel) of the outpatients. The clinical symptoms of depression group were investigated by structural interview. The depressive symptoms and depression level were evaluated by flow center depression scale (CES-D), and the characteristics of alexithymia were measured by Toronto alexithymia scale (TAS-20) in Chinese. Results: (1) there were significant differences in the scores of depression, physical symptoms, positive emotion and interpersonal relationship between the depression group and the normal control group, as well as the total score of the scale. The scores of depression in depression group were significantly higher than those in normal control group (P0. 001). (2). The scores of depression factor in male patients with depressive disorder were significantly lower than those in women (P 0.01). There were significant differences in depression factor score, somatic symptom factor score and CES-D total score among patients with depressive disorder with different educational levels. the scores of depression factor in patients with depressive disorder with educational level below primary school were significantly different. The score of somatic symptom factor and the total score of CES-D were significantly higher than those of patients with depressive disorder with other educational levels (P 0.05). There was no significant difference in depressive symptoms among patients with depressive disorder of different ages and different places of origin. (3) there were significant differences in the scores of emotional discrimination difficulty, emotional description difficulty and extroverted thinking between the depression group and the normal control group, and the total score of the scale. The scores of depression group were significantly higher than those of normal control group (P 0.01). (4). The total score of CES-D was significantly correlated with the score of emotion discrimination difficulty factor, emotion description difficulty factor and TAS-20 score of patients with depression disorder (P 0.05). Depression emotion factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroverted thinking factor score and TAS-20 total score (correlation coefficient was 0.122 卤0.169, P 0.05 or P 0.01), and there was a significant correlation between depression emotion factor score and emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score. Somatic symptom factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score (P 0.05). The positive emotion factor score was significantly correlated with the extroversion thinking factor score (P 0.05), and the interpersonal difficulty factor score was significantly correlated with the total score of TAS-20 (P 0.05). The total score of CES-D, depressive mood and somatic symptom factors in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05), and the scores of total score, depression emotion and somatic symptoms in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05). Conclusion: (1) there are gender and educational differences in the severity of depression and depressive symptoms in patients with depressive disorder, (2) patients with depressive disorder show more obvious alexithymia than healthy people, and (2) there are more obvious alexithymia in patients with depressive disorder than in healthy people. (3) the symptoms of patients with depressive disorder were related to alexithymia. Patients with depressive disorder with high alexithymia showed more serious depressive symptoms and were more likely to show somatization symptoms. Table 8, references 86
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R749.4
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