患者口腔颌面部间隙感染病原菌分布及药敏性

发布时间：2018-01-30 08:33

本文关键词： 口腔颌面部间隙感染病原菌药敏性　出处：《中华医院感染学杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨患者口腔颌面部间隙感染病原菌培养及药敏性,以期为临床口腔颌面部间隙感染预防及治疗提供依据。方法收集医院2013年1月-2015年9月204例口腔颌面部间隙感染患者临床资料,观察患者一般资料、病原菌检出类型及主要菌株药物敏感性。结果牙源性感染患者占66.18%,腺源性感染患者占29.90%,医源性感染患者占3.92%,感染部位以颌下间隙最高占59.81%,舌下间隙最低为2.45%;204例患者标本中以混合感染为主占48.04%;共培养出病原菌238株,其中革兰阳性菌147株占61.77%,革兰阴性菌91株占38.23%,其中厌氧菌56株占23.53%;药敏结果显示,葡萄球菌属对利福平敏感率较高;链球菌属对左氧氟沙星敏感率较高;铜绿假单胞菌对万古霉素敏感率高;肺炎克雷伯菌对万古霉素、亚胺培南敏感率均为100.0%;厌氧菌对甲硝唑、亚胺培南及万古霉素敏感率较高。结论患者口腔颌面部间隙感染病原菌以混合感染为主,确诊后应尽早抗炎治疗,可根据病原菌分析结果选择抗菌药物联合抗厌氧菌药物治疗,同时给予药物敏感试验检查,明确后针对性抗炎。
[Abstract]:Objective to investigate the bacterial culture and drug sensitivity of patients with oral and maxillofacial space infection. Methods the clinical data of 204 patients with oral and maxillofacial space infection from January 2013 to September 2015 were collected. The types of pathogenic bacteria and the drug sensitivity of main strains were observed. Results Odontogenic infection accounted for 66. 18%, and adenogenic infection accounted for 29.90%. Iatrogenic infection accounted for 3.92% of the patients. The infective site was 59.81 in the submaxillary space and 2.45 in the sublingual space. In 204 cases, mixed infection accounted for 48.04%. A total of 238 strains of pathogens were cultured, of which 147 were Gram-positive bacteria (61.77), 91 Gram-negative bacteria (38.23) and 56 anaerobic bacteria (23.53). The sensitivity of Staphylococcus to rifampicin was higher than that of Staphylococcus. Streptococcus is sensitive to levofloxacin. Pseudomonas aeruginosa was sensitive to vancomycin. The susceptibility rates of Klebsiella pneumoniae to vancomycin and imipenem were 100.0; Anaerobes are sensitive to metronidazole, imipenem and vancomycin. Conclusion the main pathogens of oral and maxillofacial space infection are mixed infection. According to the results of pathogenic bacteria analysis, antimicrobial agents combined with anti-anaerobic drugs can be selected, and drug sensitivity tests are also given.
【作者单位】：平顶山市第二人民医院呼吸科;平顶山市第一人民医院消化科;平顶山市第二人民医院护理部;平顶山市第一人民医院院控感办;平顶山市第二人民医院颌面外科;
【基金】：河南省科技厅科技发展计划(14A329013)
【分类号】：R782.3
【正文快照】： 内含有多种正常菌群,如机体免疫功能下降、口腔内环境改变等,均可引发条件致病菌繁殖、扩散,导致口腔颌面部间隙感染,继而引发败血症、颅内感染、血栓性静脉炎及局部脓肿等感染性病变,对患者健康及生命造成威胁[1]。感染途径主要为牙源性、腺源性、损伤性及医源性,发病后进展

【相似文献】