菌毛蛋白V型与正畸患者牙龈炎性反应的相关性

发布时间：2018-02-04 16:13

本文关键词： 正畸治疗牙龈卟啉单胞菌 FimA V型牙龈炎　出处：《山东大学学报(医学版)》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨牙龈卟啉单胞菌(P.g)的菌毛蛋白(FimA)V亚型基因表达与正畸患者牙龈炎性反应的相关性。方法随机选取61例正畸治疗前牙龈健康的患者,分别收集患者正畸治疗前和戴入矫治器后3个月的龈沟液,用PCR技术检测临床样本中的P.g和FimA V型。结果正畸治疗前与戴入矫治器后3个月的P.g检出率分别是26.23%、73.77%,两者间存在统计学差异(P0.01);FimA V型的检出率分别是9.84%、26.23%,两者间存在统计学差异(P0.05)。结论正畸患者在戴入矫治器3个月后,P.g和FimA V型的检出率都与牙龈指数呈现正相关,牙龈指数升高,且FimA V型检出率也随之增加,FimA V型可以引起正畸患者的牙龈炎性反应。
[Abstract]:Objective to study the FimA of P. gingivalis P. gr. The relationship between V subtype gene expression and gingival inflammatory response in orthodontic patients methods 61 patients with gingival health before orthodontic treatment were randomly selected. Gingival crevicular fluid was collected before orthodontic treatment and 3 months after wearing orthodontic appliance. The detection rate of P.g and FimA V in clinical samples by PCR technique was 26.23% and 73.77% respectively before orthodontic treatment and 3 months after orthodontic treatment. There was a statistical difference between the two groups (P 0.01). The detection rate of FimA V type was 9.84 and 26.23, respectively. There was a statistical difference between the two groups (P0.050.Conclusion Orthodontic patients wear orthodontic appliance for 3 months. The detection rate of P.g and FimA V type were positively correlated with gingival index, gingival index increased, and the detection rate of FimA V type also increased. FimA V type can cause gingival inflammatory response in orthodontic patients.
【作者单位】：滨州医学院口腔学院;济南市章丘区人民医院口腔科;济南市口腔医院正畸科;
【基金】：济南市科技局企业创新计划(201121038)
【分类号】：R783.5
【正文快照】： 网络出版地址:http://www.cnki.net/kcms/detail/37.1390.R.20170302.1102.008.html牙龈卟啉单胞菌(porphyromonas gingivalis,P.g)是革兰阴性专性厌氧菌,常在牙周组织疾病中检出[1-2],Tan等[3]研究表明,P.g能明显地阻止牙周膜细胞的成骨分化。P.g可以产生多种毒性因子,破坏宿

【相似文献】