韦荣球菌与龋病和链球菌间的关系

发布时间：2018-02-21 16:01

本文关键词： 韦荣球菌链球菌龋病　出处：《国际口腔医学杂志》2017年02期 　论文类型：期刊论文

【摘要】：韦荣球菌为口腔微生态的重要成员之一,在人类口腔中呈高丰度分布。韦荣球菌不能代谢糖产酸,但能代谢乳酸,这一点曾被认为对龋病的发生发展有抑制作用,但体外及动物试验对于韦荣球菌在龋病发生中的作用及其机制并未得出明确结论。近来随着口腔微生物组学研究的发展,人们发现,韦荣球菌在龋活跃者口腔中的分布较无龋者高,韦荣球菌与多种致龋菌分布呈高度相关性,韦荣球菌对变异链球菌等致龋菌有促进作用。龋病是多种微生物共同作用的结果,而韦荣球菌作为龋病相关因素不容忽视。本文就韦荣球菌在口腔中的分布、韦荣球菌与龋病的关系、韦荣球菌与链球菌的相互作用等研究进展作一综述,以剖析韦荣球菌在龋病发生发展中的作用及其机制。
[Abstract]:As one of the most important members of oral microecology, Veronella has a high abundance distribution in human oral cavity. Veronella can not metabolize sugar and acid, but can metabolize lactic acid, which has been considered to inhibit the occurrence and development of caries. However, in vitro and animal experiments have not reached a clear conclusion on the role and mechanism of Veronella in the occurrence of caries. Recently, with the development of oral microbiology, it has been found that, The distribution of Veronella in the oral cavity of active caries was higher than that of non-caries. There was a high correlation between the distribution of Veronella and many kinds of cariogenic bacteria, and the effect of Veronella on the cariogenic bacteria such as Streptococcus mutans was promoted, and caries were the result of the combined action of many microbes, such as Streptococcus mutans. The distribution of Veronella in the oral cavity, the relationship between Veronella and caries, the interaction between Veronella and Streptococcus, and so on, are reviewed in this paper. In order to analyze the role of Veronella in the occurrence and development of caries and its mechanism.
【作者单位】：口腔疾病研究国家重点实验室华西口腔医院牙体牙髓病科(四川大学);
【基金】：国家自然科学基金(81400501,81430011) 中国国际科技合作计划(2014DFE30180)~~
【分类号】：R781.1

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