SLA种植体表面喷涂钽形成纳米复合表面预防种植术后早期感染的动物体内实验研究

发布时间：2018-02-22 21:51

本文关键词： 种植体表面处理种植体周围炎　出处：《中国临床解剖学杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的探讨大颗粒酸蚀喷砂(Sandblasted/Large-grit/Acide-tched,SLA)表面处理的种植体与SLA表面喷涂钽(Ta)形成纳米复合表面的种植体对种植体周围炎发生发展的影响。方法 6只Beagle犬双侧前磨牙延期植入2种不同表面种植体。从左侧远中到右侧远中依次将植体记为1~6号,3、4号种植体设置非绑线的基线组,其余于基台颈部丝线结扎的方法建立犬种植体周围炎模型。分别在建模后四次对植体进行菌斑指数(plaque index,PI)、改良出血指数(modified Sulcus Bleeding Index,m SBI)、种植体周探诊深度(probing depth,PD)等临床指标测量,通过手术直观评价、显微CT扫描、组织学评价相结合观察种植体周骨缺损程度,对实验结果采用重复测量方差分析。结果绑线的SLA组PI、m SBI、PD、垂直缺损与水平缺损深度等指标均显著高于绑线的SLA+Ta组(P0.05);显微CT扫描和组织学评价相结合观察可见绑线的SLA组较绑线的SLA+Ta组种植体周骨缺损明显。结论 SLA表面喷涂钽形成纳米复合表面的种植体较SLA表面处理的种植体延缓种植体周围炎的发生发展并减轻其症状。
[Abstract]:Objective to investigate the effect of nano-composite implants on the occurrence and development of peri-implant inflammation in large granulated acid blast sandblasted / large scale / Acide-tched-SLA-treated implants and SLA surface sprayed tantalum. Methods six Beagle dogs with bilateral premolars were treated with delayed implantation. From the left to the right, the implants were recorded as the baseline group of 1 ~ 6 and 4, respectively. The other methods of ligation of cervical filaments of the base platform were used to establish the canine model of periimplant inflammation. The plaque index (plaque index), modified Sulcus Bleeding index (modified Sulcus Bleeding index), modified Sulcus Bleeding index (modified Sulcus), and the depth of periimplant probing were measured four times after the establishment of the model. The degree of peri-implant bone defect was observed by visual evaluation, microscopic CT scan and histological evaluation. The results of the experiment were analyzed by repeated measurement of variance. Results the vertical defect and horizontal defect depth of SLA group were significantly higher than those of SLA Ta group. The bone defect around implants in SLA group was more obvious than that in SLA Ta group. Conclusion compared with SLA implants coated with tantalum on SLA surface, nano-composite implants can delay the occurrence and development of peri-implant inflammation and alleviate its symptoms.
【作者单位】：南方医科大学南方医院口腔种植科南方医科大学口腔医学院;
【基金】：广东省科技计划项目(2013B010403012)
【分类号】：R783.6

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