肠道微生物调控骨代谢的研究进展

发布时间：2018-02-23 16:17

  本文关键词： 肠道 微生物群落 骨代谢 牙槽骨 牙周炎　出处：《国际口腔医学杂志》2017年06期 　论文类型：期刊论文

【摘要】：人类胃肠道内栖居着数量众多且种类繁杂的微生物群,肠道菌群稳态的维持对于宿主正常代谢活动的有序进行至关重要。随着人体微生物组研究的开展,肠道菌群变化对骨代谢活动的影响引起众多学者的关注。本文对肠道微生物与骨健康的关系、肠道微生物影响骨代谢的潜在机制以及肠道微生物对牙槽骨可能发挥的调控作用进行综述,以期为肠道微生物与骨代谢相关疾病的病因学研究以及疾病诊疗提供新的思路。
[Abstract]:The homeostasis of the intestinal flora is very important for the normal metabolic activities of the host. With the development of the study of human microflora, the human gastrointestinal tract is inhabited by a large number of numerous and diverse microbes. The homeostasis of the intestinal microflora is very important for the normal metabolic activities of the host. The influence of intestinal microflora on bone metabolism has attracted many scholars' attention. The relationship between intestinal microorganism and bone health is discussed in this paper. The potential mechanism of intestinal microbes affecting bone metabolism and the possible regulation of intestinal microbes on alveolar bone were reviewed in order to provide a new idea for the etiological study of intestinal microbes and bone metabolism-related diseases as well as the diagnosis and treatment of diseases.
【作者单位】： 口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院牙体牙髓病科;口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院牙周病科;口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院儿童口腔科;
【基金】：国家自然科学基金(81430011,81371135) 四川大学优秀青年学者基金(2015SCU04A16)~~
【分类号】：R780.2
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本文编号：1526828