口腔颌面部间隙感染患者的病原菌分布、临床感染特点及相关预防措施

发布时间：2018-03-05 21:29

本文选题：口腔颌面部间隙感染　切入点：病原菌　出处：《中华医院感染学杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的调查口腔颌面部间隙感染患者的病原菌分布及临床感染特点,探讨相关预防措施。方法回顾性分析2014年3月-2016年3月161例口腔颌面部间隙感染患者的临床资料。采集患者脓液标本,注入疱肉培养液管中,分别进行需氧和厌氧培养及药敏试验。结果 161例口腔颌面部间隙感染患者,感染部位以眶下间隙、颌下间隙和咬肌间隙感染为主,分别占31.7%、23.0%和13.7%;病因以牙源性感染为主,占61.5%,其次为腺源性感染和外伤性感染,分别占19.3%和10.6%;共分离出病原体423株,以需氧-厌氧混合菌感染为主,占45.4%;需氧菌感染占33.1%,以金黄色葡萄球菌最常见,占11.3%;厌氧菌感染占21.5%,以普氏菌最常见,占9.2%;金黄色葡萄球菌对环丙沙星最为敏感,耐药率为22.9%;肺炎链球菌和肺炎克雷伯菌对亚胺培南最为敏感,耐药率为8.6%和9.5%;普氏菌、梭杆菌对亚胺培南最为敏感,耐药率为6.5%和11.5%;放线菌对多粘菌素E最为敏感,耐药率为26.7%。结论医院口腔颌面部间隙感染患者以眶下间隙感染为主,牙源性感染是主要病因,需氧-厌氧混合菌感染最为常见,临床应根据其药敏和相关因素及时采取有效措施,防止病情发展。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and clinical infection in patients with oral and maxillofacial space infection. Methods the clinical data of 161 patients with oral and maxillofacial space infection from March 2014 to March 2016 were analyzed retrospectively. Results 161 patients with oral and maxillofacial space infection were mainly infected by suborbital space, submaxillary space and masseter space, accounting for 23.0% and 13.70.The main etiology was odontogenic infection. Accounted for 61.5%, followed by adenogenic infection and traumatic infection, accounting for 19.3% and 10.6 respectively. 423 strains of pathogens were isolated, mainly from aerobic and anaerobic mixed bacteria (45.4%); aerobic infections accounted for 33.1%; Staphylococcus aureus was the most common. Accounting for 11.3%; anaerobic infection accounted for 21.5%, of which Pueraria was the most common, 9.2%; Staphylococcus aureus was the most sensitive to ciprofloxacin, with a drug resistance rate of 22.90.Streptococcus pneumoniae and Klebsiella pneumoniae were most sensitive to imipenem with resistance rates of 8.6% and 9.5. Clostridium clostridium is the most sensitive to imipenem, the drug resistance rate is 6.5% and 11.5.The actinomycetes is the most sensitive to polymyxin E and the drug resistance rate is 26.70.Conclusion the infection of suborbital space is the main cause of hospital oral and maxillofacial space infection, and odontogenic infection is the main cause. Aerobic-anaerobic mixed bacteria infection is the most common clinical drug sensitivity and related factors should take timely and effective measures to prevent the development of the disease.
【作者单位】：遵义市第一人民医院口腔科;
【基金】：贵州省科学技术基金资助项目(黔科合J字LKZ(2010)12号)
【分类号】：R782.3

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