金匮肾气丸联合替硝唑治疗肾气亏损型牙周病的效果

发布时间：2018-03-10 13:15

本文选题：中西医结合　切入点：金匮肾气丸　出处：《广东医学》2015年17期 　论文类型：期刊论文

【摘要】：目的探讨金匮肾气丸联合替硝唑片中西医结合辩证施治肾气亏损型牙周病的临床疗效。方法选取经中医辩证诊断为肾气亏损的牙周病患者100例,采用中西医结合治疗,替硝唑片0.5 g/次,2次/d,口服7d,同时以金匮肾气丸汤剂1剂/d,煎服2周;金匮肾气丸汤剂2周为一疗程,连续3个疗程结束后统计疗效;疗效测定分别于治疗前、疗程结束后4、12、26和52周,分别检查记录每个受检位点的牙周检测菌斑指数(PLI)、龈沟出血指数(SBI)、牙周探诊深度(PD)、附着丧失(AL)、探诊出血(BOP)。结果疗程结束后4、12、26和52周的PLI、SBI、PD、AL、BOP疗效测定分别与治疗前对比明显改善,差异有统计学意义(P0.05);疗程结束后12、26和52周的SBI、PD、AL检测结果两两对比无明显变化(P0.05),但分别与疗程结束后4周对比有改善,差异有统计学意义(P0.05)。临床总有效率达96%。结论金匮肾气丸联合替硝唑片辩证施治肾气亏损型牙周病临床疗效显著,中期疗效更加确切稳定。
[Abstract]:Objective to investigate the clinical effect of Jinkui Shenqi Pill combined with tinidazole tablet in the treatment of periodontal disease with deficiency of kidney qi. Methods 100 cases of periodontal disease with deficiency of kidney qi diagnosed by traditional Chinese medicine were selected and treated with integrated Chinese and western medicine. Tinidazole tablet 0.5 g / d twice a day, orally for 7 days, at the same time taking Jingui Shenqi Pill 1 / d for 2 weeks, Jingui Shenqi Pill for 2 weeks as a course of treatment, counting the curative effect after three consecutive courses of treatment, the curative effect was measured before treatment, At the end of the course, 12 weeks and 52 weeks later, The periodontal plaque index (PLI), gingival sulcus bleeding index (GCI), periodontal probing depth (PD), appurative loss of ALP, and bleeding were detected at each locus, respectively. Results the therapeutic effects of PLI SBIPDP were significantly improved after treatment at the end of the treatment. The difference was statistically significant (P 0.05), the results of SBI PDAL at the end of 12 and 52 weeks had no significant change (P 0.05), but it was improved after 4 weeks of treatment, respectively, after the end of the course of treatment, there was no significant difference between the two groups, but there was no significant difference between the two groups after the end of the course of treatment. The total clinical effective rate was 96. Conclusion Jingui Shenqi Pill combined with tinidazole tablet is effective in the treatment of periodontal disease with deficiency of kidney qi.
【作者单位】：广东省佛山市中医院口腔医疗中心;
【基金】：广东省中医药局建设中医药强省科研课题(编号:2010281)
【分类号】：R781.4

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