牙周炎犬即刻种植即刻加载后种植体—骨界面骨结合的研究

发布时间：2018-04-04 00:57

  本文选题：牙周炎　切入点：即刻种植　出处：《安徽医科大学》2014年硕士论文

【摘要】：目的研究犬下前磨牙区域建立牙周炎模型后即刻种植即刻加载种植体-骨界面骨结合情况。 方法8只实验用Beagle犬，所有犬于双侧下颌前磨牙位置行丝圈结扎并辅以高糖饮食，建立犬牙周炎模型。开始建模后的第1、2、3、4周分别对所有犬行牙周探诊，建模在4周时间内完成。第5周分别给予所有犬龈上洁治及龈下刮治并控制牙周菌斑。5周后同时拔除每只犬双侧下颌第3、4前磨牙，在相应的拔牙窝选择最佳位置即刻植入DIO种植体（直径3.8mm，长度10.0mm）各1颗，同期连接基台（直径3.8mm，长度6.0mm）。术后24h内采用种植体垂直加载仪进行垂直加载，将每只犬下颌的4枚种植体按照加载力的不同分为：5N、10N、15N、对照组，加载频率为2Hz，加载时间为每日15min。加载4周及8周后各处死4只犬，制作标本，分别进行大体观察、影像学观察与分析、硬组织与形态学观察分析。 结果①各组种植体周围骨质均有吸收，其中15N加载组吸收明显并伴有Ⅱ-Ⅲ度松动。②不同加载周期，5、10N加载组较对照组在BMD方面差异有统计学意义（P0.01）。③不同加载周期，5、10N加载组较对照组在BV/TV、Tb.Th、Tb.N、Po方面差异均有统计学意义（P0.01），加载8周时，5、10N加载组与对照组在SMI方面差异有统计学意义（P0.01）。④组织切片显示不同加载期5、10N加载组较对照组新骨骨量更多，加载8周时5、10N加载组较对照组新生骨与螺纹间空隙更小。 结论在本实验条件下，不同加载周期时，加载组较对照组骨生成及骨改建更积极，表明牙周炎模型犬即刻种植后，以适当的加载力即刻加载后可获得良好的种植体-骨结合。
[Abstract]:Objective to study the bone bonding between implant-bone interface and immediate implant implantation after periodontitis model was established in canine premolar region.Methods eight Beagle dogs were used to establish a canine model of periodontitis.Periodontal diagnoses were performed in all dogs in 4 weeks after modeling, and the modeling was completed within 4 weeks.All dogs were given supragingival scaling and subgingival curettage at the 5th week, and the periodontal plaque was controlled for 5 weeks.DIO implants (3. 8mm in diameter and 10. 0mm in length) were immediately implanted in the optimal position of the extraction fossa. The abutment was connected with the abutment (3. 8mm in diameter and 6. 0mm in length) at the same time.Four mandibular implants of each dog were divided into two groups according to the different loading forces: 1: 5NX 10Nm 15N, the control group was loaded with 2Hz, and the loading time was 15min per day.After 4 weeks and 8 weeks of loading, 4 dogs were killed, and the specimens were made for gross observation, imaging observation and analysis, hard tissue and morphology observation and analysis.Results 1 the bone around implants were absorbed in each group.The absorption of 15N loading group was significantly higher than that of the control group with 鈪，

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