促牙本质再矿化的生物活性树脂研究进展

发布时间：2018-04-10 15:40

本文选题：树脂 + 生物活性　；参考：《国际口腔医学杂志》2017年04期

【摘要】：诱导混合层裸露胶原再矿化是提高树脂牙本质粘接耐久性的重要方法。然而粘接界面有限的矿化离子源限制了牙本质再矿化的临床应用。采用无机材料对粘接树脂改性,可制备出具有生物活性的树脂修复材料,这些树脂在溶液中可缓慢释放矿化离子(如Ca~(2+)、PO_4~(3-)、OH~-等),具有促进脱矿牙体组织再矿化的潜能。用于树脂改性的无机材料包括硅酸盐、磷酸钙盐、生物活性玻璃等。研究证实生物活性树脂修复材料具有促进脱矿牙本质再矿化、抑制胶原纤维降解的能力,但在树脂中添加无机材料会影响树脂的力学性能,制备具有良好力学性能的生物活性树脂是研究的重点和难点。本文将分类阐述不同生物活性树脂修复材料在牙本质再矿化中的作用。
[Abstract]:It is an important method to improve the durability of resin dentin bonding by inducing the remineralization of exposed collagen in the mixed layer.However, limited interfacial mineralized ion sources limit the clinical application of dentin re-mineralization.By modifying the adhesive resin with inorganic materials, biologically active resin restoration materials can be prepared. These resins can slowly release mineralized ions (such as Ca~(2 / P _ 4O _ 4 / O _ HH _ (-) -) in solution, which has the potential to promote the demineralization of demineralized dentin tissue.Inorganic materials used for resin modification include silicate, calcium phosphate, bioactive glass and so on.It has been proved that the bioactive resin restoration material has the ability of promoting demineralization of demineralized dentin and inhibiting the degradation of collagen fiber, but adding inorganic materials to the resin will affect the mechanical properties of the resin.The preparation of bioactive resins with good mechanical properties is an important and difficult point.In this paper, the role of different bioactive resin restoration materials in dentin remineralization is discussed.
【作者单位】：中山大学光华口腔医学院·附属口腔医院牙体牙髓病科广东省口腔医学重点实验室;
【基金】：国家自然科学基金(81100743) 广东省科技计划国际合作项目(2013B051000031) 广东省自然科学基金(2014A0303130-68)~~
【分类号】：R783.1

【相似文献】