氟化钠-壳聚糖凝胶对乳牙釉质早期龋再矿化实验观察

发布时间：2018-04-12 22:30

本文选题：壳聚糖水凝胶 + 氟化钠　；参考：《实用口腔医学杂志》2017年04期

【摘要】：目的:探讨氟化钠壳聚糖凝胶促进乳牙釉质早期龋模型再矿化的可行性。方法:乳前牙试件使用乳酸羧甲基纤维素凝胶预处理,制备早期龋模型;早期龋的乳前牙试件随机分成4组(n=6),3组分别进行氟化钠壳聚糖凝胶、壳聚糖空白凝胶、多乐氟处理,1组作为空白对照,处理完成后进行p H循环,SEM、EDS检测循环完成后的试件表面。结果:SEM观察,氟化钠壳聚糖凝胶能更好的保护釉质表层结构不受破坏,而多乐氟和空白对照组,则表现出釉质表层的崩解。同时氟化钠壳聚糖凝胶有更多的矿化物结晶在釉质表面形成。EDS检测钙离子的沉积比例,氟化钠壳聚糖凝胶组明显多于其余各组(P0.05)。结论:氟化钠壳聚糖凝胶可以提高乳前牙早期龋的再矿化水平。
[Abstract]:Objective: to investigate the feasibility of sodium fluoride chitosan gel in promoting the early caries of primary enamel.Methods: the model of early caries was prepared by pretreatment of the premolars with carboxymethylcellulose lactate gel, and the early caries were randomly divided into 4 groups: sodium fluoride chitosan gel and chitosan blank gel.The surface of the specimen was detected by PH-cycle SEMM-EDS after the treatment was completed in group 1 treated with doloflurane as a blank control.Results the results showed that sodium fluoride chitosan gel could better protect the enamel layer from destruction, while Dorafur and blank control group showed the disintegration of enamel surface layer.At the same time, sodium fluoride chitosan gel had more mineralized crystals on enamel surface. EDS was used to detect Ca ~ (2 +) deposition ratio. Sodium fluoride chitosan gel group was significantly more than other groups (P 0.05).Conclusion: sodium fluoride chitosan gel can improve the level of early caries in primary teeth.
【作者单位】：南京医科大学口腔疾病研究江苏省重点实验室南京医科大学口腔医学院儿童口腔科预防口腔科;南京市口腔医院儿童口腔科;
【基金】：江苏省卫生计生委预防医学科研课题(编号:Y2015051) 江苏高校品牌专业建设工程资助(编号:PPZY2015B163)
【分类号】：R781.1

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