复发性阿弗他溃疡患者心理及口腔健康相关生活质量的研究

发布时间：2018-04-17 18:29

  本文选题：复发性阿弗他溃疡 + 口腔健康相关生活质量　； 参考：《大连医科大学》2017年硕士论文

【摘要】：研究目的:通过口腔健康影响程度量表(OHIP-14中文版)评估复发性阿弗他溃疡(RAU)患者的口腔健康相关生活质量(oral health related quality of life,OHRQOL),并通过焦虑自评量表(SAS)、抑郁自评量表(SDS)、疼痛度视觉类比标尺值(VAS值)及OHIP-14评估RAU患者OHRQOL与其心理健康状况之间的相关性。通过对数据的研究,给RAU的病因及发病机制作理论支持,以期优化RAU的疗效,给临床治疗提供强有力的支持。研究方法:选取于大连医科大学附属第一医院口腔门诊就诊的111例RAU病人作为RAU组,再选取在年龄、性别、文化水平等方面相仿的100例非RAU个人作为对照组。使用OHIP-14、SAS、SDS对111例RAU患者及100例非RAU对照组人群作调查,同时写下RAU患者的VAS值、溃疡个数与位置,随后收回调查问卷,再对调查问卷的有效性作以评估。在处理最终数据时选择SPSS 22.0软件。研究结果:1.被调查的111例RAU患者中,性别为女的有77例(69.4%),性别为男的有34例(30.6%),女性明显多于男性;年龄15～75岁,平均年龄38.3±14.4岁,其中15～30岁有39例,30～45岁有36例,45～60岁有27例,60～75岁有9例;轻型复发性阿弗他溃疡(MiRAU)86例,腺周口疮(MaRAU)11例,口炎型口疮(HU)14例;溃疡发生的位置在舌部占38.3%,唇部占25.5%,牙龈占14.9%,颊部占12.3%,口底黏膜占5.0%,硬腭占4.0%;有明显家族遗传倾向的有12例;与月经周期有关的有13例;戒烟后加重的有3例。2.被调查的111例RAU患者和对照组的0HIP-14总得分的中位数分别是22和10,RAU组明显高于对照组,而且在功能限制、生理性疼痛、生理障碍、心理障碍这4个领域也较对照组差异明显。3.RAU患者OHIP-14各条目中表现为负面影响的个体所占比例中除了功能限制、生理性疼痛、生理障碍、心理障碍四个领域差异明显外,在"觉得生活不是那么令人满意"方面的个体所占比例也比对照组高,差异较大。4.RAU患者的OHRQOL越差,疼痛便会随之增加,焦虑和抑郁的症状也随之加重;RAU患者的OHIP-14总得分与VAS分值、SAS分值、SDS分值均呈正相关。研究结论:1.RAU对患者的OHRQOL有着消极的影响。2.RAU患者的OHRQOL与VAS分值、SAS分值、SDS分值呈正相关。因此应该首先解决RAU造成的口腔功能障碍问题,然后有所侧重地关注患者的心理、工作、社会环境对疾病的干扰,使生理、心理治疗相结合,提高患者的心理健康程度,释放压力,从而改善RAU病人的生活质量。
[Abstract]:Objective: to evaluate the oral health related quality of life (QOL) in patients with recurrent aphthous ulcer (Rau) by OHIP-14), and to evaluate the quality of oral health related quality of life (QOL) in patients with recurrent aphthous ulcer.Visual analogies (VAS) and OHIP-14 were used to evaluate the correlation between OHRQOL and mental health in patients with RAU.In order to optimize the curative effect of RAU and provide strong support for clinical treatment, the study of data provides theoretical support for the etiology and pathogenesis of RAU.Methods: one hundred and eleven patients with RAU were selected as RAU group in the oral clinic of the first affiliated Hospital of Dalian Medical University, and 100 non- patients with similar age, sex and education level were selected as the control group.Using OHIP-14 sasco SDS to investigate 111 cases of RAU and 100 cases of non- control group. At the same time, write down the VAS value, the number and location of ulcers in RAU patients, and then withdraw the questionnaire, and then evaluate the effectiveness of the questionnaire.Select SPSS 22. 0 software when processing final data.The result of the study was: 1.Among the 111 RAU patients investigated, 77 cases were female, 34 cases were male, the age was 1575 years old, the average age was 38.3 卤14.4 years old, 39 cases were 1530 years old, 36 cases were 4560 years old, 27 cases were 6060 years old, 9 cases were 75 years old, the age was 1575 years old with an average age of 38.3 卤14.4 years.There were 86 cases of mild recurrent aphthous ulcer with MiRAUU, 11 cases with periglandular aphthous ulcer and 14 cases with stomatitis type of stomatitis, the location of ulcer was 38.3% in the tongue, 25.5% in the lip, 14.9% in the gingiva, 12.3 in the buccal part, 5.0 in the fundus mucosa and 4.0 in the hard palate. 12 cases had obvious familial genetic tendency.There were 13 cases associated with menstrual cycle and 3 cases aggravated after quitting smoking.The median of total 0HIP-14 scores of 111 RAU patients and control group were 22 and 10, respectively, which were significantly higher than those in the control group, and were significantly higher than those in the control group in terms of functional limitation, physiological pain, and physiological disorders.Compared with the control group, there were significant differences in the proportion of individuals with negative effects in the OHIP-14 of patients with Rau, except for functional limitation, physiological pain, physiological disorder and psychological disorder, among which there were significant differences in the four areas, including functional limitation, physiologic pain, physiological disorder and psychological disorder.The proportion of individuals who "felt less satisfied with life" was also higher than that in the control group. 4. The worse the OHRQOL of patients with Rau, the higher the pain.The symptoms of anxiety and depression also aggravated. The total score of OHIP-14 was positively correlated with the score of VAS.Conclusions 1. Rau has a negative effect on the OHRQOL of patients. 2. There is a positive correlation between OHRQOL and VAS scores in patients with Rau.Therefore, we should first solve the problem of oral dysfunction caused by RAU, and then pay more attention to the disturbance of patients' psychology, work and social environment to the disease, so as to combine physiology and psychotherapy to improve the patients' mental health.Release pressure to improve the quality of life of RAU patients.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R781.5
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本文编号：1764760