口腔颌面部间隙感染的病原学分析及危险因素研究

发布时间：2018-04-17 20:13

  本文选题：口腔颌面部间隙 + 感染　； 参考：《中华医院感染学杂志》2017年13期

【摘要】：目的探讨口腔颌面部间隙感染的病原学分布,并分析感染出现的危险因素。方法选取2014年1月-2016年6月医院收治的患有口腔疾病的患者437例作为研究对象,调查住院期间患者口腔颌面部间隙的感染率,通过对患者口腔颌面部间隙感染的分泌物进行培养及鉴定,分析感染的病原学分布,细菌培养采用需氧培养和厌氧培养两种模式,运用单因素及多因素Logistic线性回归分析方法探讨感染的危险因素。结果 437例患者发生口腔颌面部间隙感染39例,感染率为8.9%,共检出病原菌73株,其中需氧菌37株,厌氧菌15株,兼氧菌21株,感染来源主要为牙源性感染;单因素分析结果表明:高龄(≥60岁)、合并糖尿病、应用激素、医源性操作不当等情况的患者相对而言更容易出现口腔颌面部间隙感染,差异有统计学意义(P0.05),logistic回归模型多因素分析,显示:高龄(≥60岁)、合并糖尿病、医源性操作不当为口腔颌面部感染的独立危险因素,应用激素与感染无明显相关性。结论口腔颌面部间隙感染的影响因素较多,最常见的病原菌为金黄色葡萄球菌和草绿色链球菌,临床上应该针对高危因素采取对应预防措施,积极预防口腔颌面部间隙感染的发生。
[Abstract]:Objective to investigate the etiological distribution of oral and maxillofacial space infection and to analyze the risk factors of infection.Methods from January 2014 to June 2016, 437 patients with oral diseases were selected to investigate the infection rate of oral and maxillofacial space.Through the culture and identification of the secretions from oral and maxillofacial space infection, the etiological distribution of the infection was analyzed. The bacterial culture was carried out by aerobic culture and anaerobic culture.Univariate and multivariate Logistic linear regression analysis was used to study the risk factors of infection.Results 39 cases of oral and maxillofacial space infection were found in 437 patients, the infection rate was 8.9%. A total of 73 strains of pathogenic bacteria were detected, including 37 strains of aerobic bacteria, 15 strains of anaerobes and 21 strains of facultative bacteria. The main source of infection was odontogenic infection.Univariate analysis showed that older patients (鈮，

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