种植体龈下菌群构成情况分析

发布时间：2018-04-19 18:20

本文选题：种植体周围炎 + 菌群　；参考：《现代预防医学》2014年19期

【摘要】：目的了解种植体龈下菌群的构成情况,分析不同种植体龈下菌群构成的差异,从而探讨种植体周围炎发生与菌群变化的关系。方法选择我院口腔科进行义齿种植的患者作为研究对象,根据改良菌斑指数(modified Plaque Index,mPLI)、牙龈出血指数(Gingival Blood Index,GBI)及种植体周围袋深度(Peri-implant Probing pokect Depth,PPD)等指标将研究对象划分为健康种植体(一组)及炎症种植体(二组)两组,分析两组患者种植体周围菌群的检出及构成情况。结果本次共检查的66颗种植体中,有益菌血链球菌一组检出率高于二组、小韦荣菌在两组间无差异;而致病菌具核梭杆菌、中间型普氏菌和变黑普雷沃菌检出率二组高于一组,牙龈卟啉菌在两组间的检查率无差异。一组和二组各类菌群菌落形成单位的构成比差异具有统计学意义(P0.05),两组的菌群分布不同,一组患者革兰阳性兼性厌氧菌如血链球菌及其与链球菌的比例较高,而革兰阴性厌氧杆菌如具核梭杆菌、变黑普雷沃菌所占比例较低,而二组则呈相反的分布状况。结论种植体周围炎的发生与种植体周围菌群平衡破坏有一定的关系,龈下菌群革兰阳性兼性厌氧链球菌比例的降低及革兰阴性厌氧杆菌比例的升高是导致菌群平衡破坏的主要原因。
[Abstract]:Objective to understand the composition of subgingival flora of implants and analyze the differences of subgingival flora in different implants, so as to explore the relationship between the occurrence of peri-implant inflammation and the changes of the subgingival flora.Methods the patients with denture implantation in our hospital were selected as the research objects.According to the indexes of modified Plaque index, gingival Blood index and Peri-implant Probing pokect DepthPPDs, the subjects were divided into two groups: healthy implant (group 1) and inflammatory implant group (group 2).The detection and composition of bacteria around implants in two groups were analyzed.Results the positive rate of Streptococcus sanguis was higher in the first group than in the two groups, but there was no difference between the two groups, while the detection rate of the pathogenic bacteria was higher in the two groups than that in the first group.There was no difference in the detection rate of porphyria gingivalis between the two groups.The composition ratio of colony forming units in one group and two groups was significantly different (P 0.05). The distribution of bacteria in two groups was different. The proportion of Gram-positive and facultative anaerobic bacteria such as Streptococcus sanguis and its proportion to streptococcus were higher in one group.However, the proportion of Gram-negative anaerobic bacilli such as Clostridium nucleatum was lower, but the distribution of the two groups was opposite.Conclusion the occurrence of peri-implant inflammation is related to the disruption of the balance of the flora around the implant.The decrease of subgingival Gram-positive facultative streptococcus and the increase of Gram-negative anaerobic bacteria were the main causes of the disruption of the flora balance.
【作者单位】：德阳市第二人民医院口腔科;德阳市第二人民医院神经外科;德阳市第二人民医院神经科;成都军区机关医院口腔科;
【基金】：四川省卫生厅重点科技项目(120419) 德阳市重点科技项目(2012SZ044-1)
【分类号】：R783.6

【共引文献】