口腔扁平苔藓患者免疫功能状况与临床特征相关性分析

发布时间：2018-05-09 08:50

本文选题：口腔扁平苔藓 + 免疫功能　；参考：《深圳中西医结合杂志》2016年09期

【摘要】：目的:分析口腔扁平苔藓患者免疫功能与临床特征的相关性。方法:选取102例口腔扁平苔藓患者,其中38例网纹型口腔扁平苔藓患者,64例充血糜烂型口腔扁平苔藓患者,检测所有患者的免疫功能状况。结果:口腔扁平苔藓患者的CD3~+、CD4~+、Ig A、C3水平降低,CD19~+、Ig G、Ig M、CH50水平升高,差异具有统计学意义(P0.05);对于网纹型口腔扁平苔藓患者的CD16~++56~+、CD4~+/CD8~+水平降低,充血糜烂型口腔扁平苔藓患者的CD8+水平降低,差异具有统计学意义(P0.05);充血糜烂型口腔扁平苔藓患者的CD3~+、CD8~+水平均显著低于网纹型口腔扁平苔藓,而CD4~+/CD8~+水平显著高于网纹型口腔扁平苔藓,差异具有统计学意义(P0.05)。结论:口腔扁平苔藓患者存在不同程度的免疫功能紊乱,体液免疫功能亢进为主;不同类型的口腔扁平苔藓患者的免疫功能状况存在差异性。
[Abstract]:Objective: to analyze the correlation between immune function and clinical features in patients with oral lichen planus (OLP). Methods: 102 patients with oral lichen planus including 38 patients with reticulated oral lichen planus and 64 patients with congestive and erosive oral lichen planus were selected. Results: in patients with oral lichen planus, the level of CD3 ~ + CD4 ~ + Ig A3 decreased and the level of CD19 ~ + Ig / Ig MU CH50 increased, the difference was statistically significant (P < 0.05), and the level of CD16 ~ 56 ~ + CD4 ~ / CD8 ~ in reticulated patients with oral lichen planus was decreased, and the level of CD16 ~ 56 ~ / CD8 ~ was decreased in patients with oral lichen planus. The CD8 level of patients with congestive and erosive oral lichen planus was significantly lower than that of reticulated oral lichen planus (P 0.05), and the level of CD3 ~ + CD8 ~ was significantly lower in patients with congestive and erosive oral lichen planus than in reticulated oral lichen planus. The level of CD4 ~ / / CD8 ~ was significantly higher than that of reticulated oral lichen planus (P 0.05). Conclusion: the patients with oral lichen planus (OLP) have different immune function disorders, but the humoral immune function is mainly hyperactive, and the immune function of patients with different types of oral lichen planus (OLP) is different.
【作者单位】：罗定市人民医院;
【分类号】：R781.5

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