肿瘤患者口腔感染真菌分布与药敏分析

发布时间：2018-05-29 02:31

本文选题：肿瘤患者 + 口腔感染　；参考：《中华医院感染学杂志》2016年19期

【摘要】：目的研究肿瘤患者口腔感染真菌分布及敏感性,为临床抗真菌药物的选择提供依据。方法选取2014年12月-2015年12月医院口腔科诊治82例肿瘤真菌感染患者临床资料,采集患者标本,分析肿瘤患者口腔感染真菌分布及其对抗真菌药物的敏感性,数据采用SPSS 18.0软件进行统计分析。结果 82例口腔真菌感染肿瘤患者的科室分布相对较广,排前3位的科室分别为老年科、ICU及内分泌科,分别占31.71%、28.05%及12.20%;肿瘤口腔感染患者中共分离出真菌103株,排在前3位的分别为白色假丝酵母菌、热带假丝酵母菌以及光滑假丝酵母菌,分别占50.49%、20.39%以及12.62%;白色假丝酵母菌、热带假丝酵母菌及光滑假丝酵母菌对两性霉素B敏感率均为100.00%。结论肿瘤患者口腔感染的真菌相对复杂,应加强真菌的分离、鉴定,并根据真菌类型进行药敏试验,选择敏感抗菌药物。
[Abstract]:Objective to study the distribution and sensitivity of oral fungal infection in tumor patients and to provide evidence for the selection of antifungal drugs. Methods from December 2014 to December 2015, the clinical data of 82 patients with tumor fungal infection were collected, and the distribution of oral infection fungi and the sensitivity of antifungal drugs were analyzed. The data were analyzed by SPSS 18.0 software. Results the distribution of 82 patients with oral fungal tumor was relatively wide. The top 3 departments were geriatric ICU and endocrine department, accounting for 31.71% and 12.20% respectively, 103 strains of fungi were isolated from patients with oral infection. The top three were Candida albicans, Candida tropicalis and Candida smooth, accounting for 50.4920.39% and 12.62%, respectively, while Candida albicans, Candida tropicalis and Candida smooth were sensitive to amphotericin B. Conclusion the fungus of oral infection in tumor patients is relatively complex. The isolation and identification of fungi should be strengthened, and the drug sensitivity test should be carried out according to the types of fungi, and sensitive antimicrobial agents should be selected.
【作者单位】：莱芜市人民医院口腔科;
【基金】：山东省口腔生物医学重点实验室开放课题基金资助项目(SDKQ201404)
【分类号】：R730.5;R781

【相似文献】