含氟涂料和含氟牙膏对釉面再矿化和抗酸作用的实验研究

发布时间：2018-05-30 13:41

本文选题：牙釉质 + 再矿化　；参考：《实用口腔医学杂志》2014年05期

【摘要】：目的:观察含氟涂料与含氟牙膏对釉质表面再矿化和抗酸作用。方法:取牛恒切牙制备釉质片;统一酸蚀脱矿后随机分为4组(n=3);分别为生理盐水(A组对照)、Duraphat含氟涂料(B组)、Fluor Protector含氟涂料(C组)、含氟牙膏规律处理(D组);处理期间标本置于人工唾液孵育2周;再次酸蚀;各阶段均用显微硬度仪测定釉面显微硬度、扫描电镜观察釉面,图像分析电镜下釉面微孔隙面积差异;统计分析。结果:首次酸蚀后釉面明显脱矿。分组处理2周,A组釉面再矿化不明显;B组和C组釉面形成涂料保护层;D组釉面可见明显再矿化。再次酸蚀后:A组和D组显微硬度下降,B组和C组涂料保护层有明显抗酸作用。再次酸蚀后,A组和D组釉面微孔隙面积增加(P0.05),但D组小于A组(P0.05);B组、C组无显著变化(P0.05)。结论:含氟涂料在釉面形成保护层,具有抗酸蚀和促进釉面再矿化作用;含氟牙膏能促进脱矿釉面再矿化,抗酸作用较弱。
[Abstract]:Objective: to observe the effect of fluorine paint and fluoride toothpaste on surface mineralization and acid resistance of enamel. Methods: enamel tablets were prepared from bovine permanent incisors. After unified acid etching demineralization, the samples were randomly divided into 4 groups: normal saline group A, control group B, fluor Protector fluorinated paint group C, fluoridated toothpaste regular treatment group D, specimen incubated with artificial saliva for 2 weeks; The microhardness of glaze surface was measured by microhardness instrument, the glaze surface was observed by scanning electron microscope, and the difference of micropore area of glaze surface under image analysis electron microscope was analyzed statistically. Results: the enamel was demineralized obviously after the first etching. The remineralization of enamel in group A was not obvious in group A and group C in group B and group C, respectively. The microhardness of group A and D decreased after reetching. The protective coatings of group B and group C had obvious acid resistance. After reetching, the enamel micropore area of group A and group D increased P0.05, but that of group D was smaller than that of group A and group B, but there was no significant change in group C (P 0.05). Conclusion: fluorine-containing coatings form protective layer on glaze surface, which can resist acid corrosion and promote remineralization of enamel surface, and fluoride toothpaste can promote demineralization of demineralized enamel surface, but its anti-acid effect is weak.
【作者单位】：第四军医大学口腔医学院
【基金】：陕西省社发攻关项目(编号:2011K12-40) 西安市医疗卫生应用研究项目(编号:SF1208)
【分类号】：R781.1

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