儿童颌下腺滑膜肉瘤1例并文献复习
发布时间:2018-06-04 00:00
本文选题:颌下腺肿瘤 + 滑膜肉瘤 ; 参考:《临床与实验病理学杂志》2015年04期
【摘要】:目的探讨滑膜肉瘤(synovial sarcoma,SS)的临床病理学特征、影像学表现、诊断及鉴别诊断。方法对1例4岁儿童颌下腺SS进行回顾性分析,并复习相关文献。结果患儿B超示左颌下混合性包块,MIR示类圆形团块状软组织影,呈均匀等信号,局部牙槽骨可见骨质破坏。镜检:肿瘤细胞梭形,呈束状、漩涡状排列且相互交叉。细胞丰富密集,异型性不明显,核呈短梭形,核分裂象少见。间质血管呈裂隙状,管壁薄。免疫表型:部分肿瘤细胞CK(AE1/AE3)和CD99呈阳性,大部分肿瘤细胞EMA和vimentin呈阳性,BCL-2弥漫阳性,CD34、CD68、Pan-mel、SMA等均阴性。结论发生于颌下腺的SS易误诊,结合影像学表现、组织学形态及免疫表型可确诊。
[Abstract]:Objective to investigate the clinicopathological features, imaging features, diagnosis and differential diagnosis of synovial sarcoma (SSS). Methods A 4-year-old child with SS in the submandibular gland was retrospectively analyzed and the related literature was reviewed. Results B-mode ultrasound showed mixed mass of left submaxillary mass (Mir) showed round mass of soft tissue with homogeneous signal intensity and bone destruction in local alveolar bone. Microscopic examination: tumor cells are fusiform, bunchy, swirling and intersecting. The cells are abundant and dense, the heterogeneity is not obvious, the nucleus is short fusiform, and the mitosis is rare. The interstitial vessels were fissured and the wall was thin. Immunophenotype: some tumor cells were positive for CKE 1 / AE3) and CD99, and most of tumor cells were positive for EMA and vimentin. Conclusion SS in submandibular gland is easy to be misdiagnosed, and combined with imaging findings, histological morphology and immunophenotype can be diagnosed.
【作者单位】: 第四军医大学西京医院病理科;
【分类号】:R739.8
【参考文献】
相关期刊论文 前2条
1 陈煜,陈伟高,余智华;63例滑膜肉瘤的临床分析[J];江西医学院学报;2005年05期
2 魏永昆,朱虹光,周平,许祖德,王坚,朱雄增;滑膜肉瘤32例临床病理分析[J];诊断病理学杂志;2002年02期
【共引文献】
相关期刊论文 前10条
1 黄智勇;蒋曦;王全;;49例躯体滑膜肉瘤的临床综合治疗分析[J];重庆医学;2011年34期
2 沈兵;陆亚平;;单相纤维型滑膜肉瘤临床病理分析[J];临床医学;2012年02期
3 刘贵秋;张勤;温丽坤;马U,
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