Composan protect脱敏剂治疗牙本质过敏症的临床疗效观察

发布时间：2018-06-17 06:00

本文选题：Composan + protect脱敏剂　；参考：《大连医科大学》2014年硕士论文

【摘要】：目的：本文以病例报道的形式将Composan protect脱敏剂与MS Coat和75%氟化钠甘油糊剂脱敏剂治疗牙本质过敏症的临床疗效进行对比，观察术后即刻、1个月和6个月的临床疗效有效率，为Composan protect脱敏剂的临床应用提供相关依据。方法：收集临床病例诊断为牙本质过敏症的患者40名，共有患牙60例，均为牙合面磨耗的活髓磨牙，随机分成A、B、C三组，每组各20例。所有患者身体健康、无药物过敏，具有良好理解能力，能配合治疗，且就诊前未服用影响牙髓感受器的药物；患牙经临床检查确诊为牙本质过敏症，且半年内未受过外伤，未曾接受过任何脱敏、正畸、牙周治疗，同时排除楔状缺损、龋病、充填体、牙髓病、根尖周病、牙周病等影响临床疗效评价的疾病。脱敏治疗前、后及复诊时均采用探诊和冷空气刺激两种方法检查牙本质过敏区，并用数值分级测评法(NRS)评价患者疼痛程度。脱敏时先清洁牙面，隔湿、干燥后，用三种脱敏剂分别对患牙进行治疗。A组：用Composan protect脱敏剂涂擦过敏区20s，气枪轻吹使其分散均匀，光固化10s，重复操作一遍；B组：用MS Coat脱敏剂涂擦过敏区30s，气枪轻吹5s，重复操作一遍；C组：用75%氟化钠甘油糊剂涂擦过敏区2min。三组脱敏后即刻检查疼痛程度，记录NRS数值。嘱患者10min内不漱口，1h内不进食，12h内不刷牙，分别于1个月、6个月后复诊，复诊时再次检查疼痛程度，记录NRS数值。通过统计NRS数值得出不同脱敏剂在不同时期的有效率，再进行统计学分析。患者复诊期间不能接受实验之外的脱敏治疗，亦不可进行正畸、牙周、充填修复等影响牙齿敏感度测评的治疗；同时告知患者，如有不适，，及时就诊。结果：治疗后即刻疗效，A、B、C三组有效率分别为95%、85%和55%，A组与B组比较，差异无统计学意义（P0.05），A组与C组、B组与C组比较，差异有统计学意义（P0.05)；治疗后1个月疗效，A、B、C三组有效率分别为90%、80%和50%，A组与B组比较，差异无统计学意义（P0.05），A组与C组、B组与C组比较，差异有统计学意义（P0.05)；治疗后6个月疗效，A、B、C三组有效率分别为85%、55%和20%，三组之间两两比较，差异均有统计学意义（P0.05）。结论：在即刻疗效和1个月疗效方面，Composan protect脱敏剂和MS Coat脱敏剂均优于75%氟化钠甘油糊剂；在6个月疗效方面，Composan protect脱敏剂优于MS Coat脱敏剂和75%氟化钠甘油糊剂。
[Abstract]:Objective : In this paper , the clinical curative effect of sensitizing agent and MS Coat and 75 % sodium fluoride glycerol paste desensitizer in treating dentin hypersensitivity were compared in the form of case report , and the clinical curative effect of immediate , 1 month and 6 months after operation was observed .

Methods : 40 patients with dentin hypersensitivity were collected from clinical cases . 60 cases of teeth were randomly divided into three groups : A , B and C . All patients had good physical health and no drug allergy .
The patient was diagnosed as dentin hypersensitivity by clinical examination , and had not received any desensitizing , orthodontist and periodontal treatment in half a year . The patients were treated with three kinds of desensitizing agents before , after and after desensitizing .
Group B : Apply the MS Coat desensitizing agent to the sensitive area for 30s , and the air gun shall be gently blown for 5s , and the operation shall be repeated again ;
Group C : 2 minutes of allergy was applied with 75 % sodium fluoride glycerin paste . The pain degree was examined immediately after three groups of desensitizing . The patients were not allowed to wash their teeth within 10 minutes . The pain level was re - examined at 1 month and 6 months .
At the same time , inform the patient , if there is discomfort , go to the doctor in time .

Results : The effective rates after treatment were 95 % , 85 % and 55 % in group A , B and C , respectively . There was no significant difference between group A and group B ( P0.05 ) .
The effective rates of group A , B and C were 90 % , 80 % and 50 % in group A , group A and group B , respectively . There was no significant difference between group A and group B ( P0.05 ) .
The effective rates were 85 % , 55 % and 20 % in group A , B and C after 6 months of treatment . There were significant differences between the three groups ( P0.05 ) .

Conclusion : Compared with 75 % sodium fluoride glycerol paste in immediate curative effect and 1 month efficacy , both protect desensitizer and MS Coat desensitizer are better than 75 % sodium fluoride glycerol paste .
In the 6 - month efficacy , the sensitizing agent was superior to the MS Coat desensitizing agent and 75 % sodium fluoride glycerol paste .
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R781.2

【参考文献】