腮腺基底细胞腺瘤9例临床分析

发布时间：2018-06-22 02:10

本文选题：基底细胞腺瘤 + 腮腺　；参考：《临床耳鼻咽喉头颈外科杂志》2014年14期

【摘要】：目的:提高对腮腺基底细胞腺瘤(BCA)临床特点、影像学特征及病理特点的认识。方法:收集、分析9例腮腺BCA的临床表现、CT及MRI特征、病理组织化学及免疫组织化学检测结果、手术治疗效果资料。结果:女性多见(男女之比2∶7),平均发病年龄55.2岁,临床表现为腮腺区无痛性肿块。影像特征为肿块位于腮腺浅叶,呈类圆形、无分叶、边界清晰,最大径小于30mm。7例CT平扫,5例示稍高软组织密度影,2例内部发生囊变。肉眼观察肿瘤质地中等,剖面呈灰白色,其中2例发生囊性变;8例包膜完整,1例包膜受侵犯。镜下观察肿瘤实质主要由基底样细胞组成,周边的肌上皮样细胞呈栅栏式排列。间质内缺乏黏液、软骨样的非上皮样物质。有基底膜样结构将肿瘤实质与间质分隔。免疫组织化学检测示基底样细胞CKpan(+)、CD117(+)、CKL(+);肌上皮样细胞P63(+)、SMA(+)、calponin(+);Ki67指数0~4%。所有病例行腮腺浅叶切除加肿瘤切除术,术后随访无复发或恶变。结论:腮腺BCA有特征性的影像学和病理学特点,术后预后良好。
[Abstract]:Objective: to improve the understanding of clinical, imaging and pathological features of basal cell adenoma (BCA) of parotid gland. Methods: the CT and MRI features of 9 cases of parotid BCA were collected and analyzed. Results: the average age of onset was 55.2 years old. The clinical manifestation was painless mass in parotid area. The imaging features were as follows: the mass was located in the superficial lobe of the parotid gland, which was round, without lobes, with a clear boundary, and the maximum diameter was smaller than that in 30mm.7. In 5 cases, cystic degeneration was found in 2 cases with slightly higher soft tissue density in 5 cases. According to the naked eye, the tumor was of medium texture and grayish white profile, of which 2 cases had cystic degeneration, 8 cases had intact capsule and 1 case had capsule invasion. The tumor parenchyma was mainly composed of basal-like cells and the surrounding myoepithelioid cells were arranged in a palisade-like manner. There is a lack of mucus, chondroid-like non-epithelioid substances in the interstitium. A basement membrane like structure separates the tumor's parenchyma from the stroma. Immunohistochemical examination showed that basal cell CKpan () CD117 () and CKL (); myoepithelioid cell p63 () SMA () calponin () Ki 67 index 0 ~ (4). All cases were treated with superficial parotid lobectomy and tumor resection. Conclusion: BCA of parotid gland has characteristic imaging and pathological features and good prognosis after operation.
【作者单位】：南京医科大学附属无锡市第二人民医院耳鼻咽喉-头颈外科;南京医科大学附属无锡市第二人民医院口腔科;
【基金】：南京医科大学科技发展基金重点项目(No:2012NJMU246)
【分类号】：R739.87

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