下颌三焦点牵张成骨整复颏部缺损牵张区新生骨生物力学变化

发布时间：2018-06-22 19:52

本文选题：牵张成骨 + 下颌骨　；参考：《中国现代医学杂志》2014年12期

【摘要】：目的研究下颌三焦点牵张成骨整复颏部缺损牵张区新生骨生物力学变化。方法选取4只成年恒河猴,通过下颌前份骨截除术形成颏部正中联合骨缺损。在两侧下颌体部各制备一个输送盘,并用自行研制的多平面牵张装置使双侧输送盘向前内方向缓慢移动并在颏部正中对接以修复颏部骨缺损。牵张结束后16周处死所有动物。通过INSTRON 8874生物力学测试系统分析测定新生骨生物力学性质。结果牵张结束后16周牵张成骨区新生骨与非牵张区下颌骨体部正常骨组织相对照,抗压缩和拉伸最大应变均无明显差异。结论运用三焦点牵张成骨术整复颏部缺损牵张结束后16周牵张成骨区新生骨骨密度接近下颌骨体部正常骨组织,基本满足下颌骨功能需要。
[Abstract]:Objective to study the biomechanical changes of mandibular trifocal distraction osteogenesis in the distraction region of mental defect. Methods four adult rhesus monkeys were selected to form bone defect of median mental joint by mandibular anterior osseotomy. A conveyer disc was prepared in each of the lower jaw bodies. A multi-plane distraction device was developed to make the bilateral transport disc move slowly forward and inward direction and docking in the middle of the mental region to repair the mental bone defect. All animals were killed 16 weeks after distraction. The biomechanical properties of new bone were analyzed by using Instron 8874 biomechanical test system. Results 16 weeks after distraction, there was no significant difference in the compressive and tensile maximum strain between the new bone in the distraction osteoblast and the normal bone in the mandibular body in the non-distraction area. Conclusion the bone mineral density of the new bone in the distraction osteoblast region is close to the normal bone tissue of the mandibular body 16 weeks after the distraction osteogenesis of the mental region is repaired by trifocal distraction osteogenesis, which basically meets the functional needs of the mandible.
【作者单位】：浙江省宁波市宁波一院口腔科;四川大学华西口腔医学院;
【基金】：浙江省自然科学基金资助项目(No:LY12H14002) 宁波市自然科学基金资助项目(No:2013A610260)
【分类号】：R782.2

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