C-反应蛋白在牙源性间隙感染中的临床意义

发布时间：2018-08-11 21:36

【摘要】：目的探讨C-反应蛋白(CRP)在牙源性间隙感染病程中的临床应用价值。方法于入院时、入院第3天、出院前检测40例牙源性间隙感染患者CRP并进行血细胞分析,观察CRP在感染不同阶段动态变化规律,比较CRP与白细胞计数(WBC)、中性粒细胞百分比(N%)的敏感性,以及脓肿切开与否的情况下患者间CRP变化的差异性。结果所有患者治疗前后CRP、WBC及N%比较,差异均有统计学意义(P0.05)。入院时所有患者CRP、WBC、N%阳性率差异有统计学意义(P0.05)。出院时所有患者CRP、WBC、N%阳性率差异无统计学意义(P0.05)。治疗前脓肿切开引流组与非脓肿切开引流组CRP差异有统计学意义(P0.05),治疗后两组CRP差异无统计学意义(P0.05)。结论 (1)CRP可作为反映牙源性间隙感染病程中的动态观察敏感指标之一;(2)动态检测CRP、WBC、N%变化对于指导牙源性间隙感染患者临床用药及判断病情转归有一定指导意义。
[Abstract]:Objective to evaluate the clinical value of C-reactive protein (CRP) in the course of odontogenic space infection. Methods CRP was detected in 40 patients with odontogenic space infection at admission and on the third day of admission, and blood cell analysis was performed to observe the dynamic changes of CRP in different stages of infection. To compare the sensitivity of CRP with (WBC), neutrophil percentage (N%) in leukocyte count, and the difference of CRP changes between patients with abscess or not. Results there were significant differences in WBC and N% between all patients before and after treatment (P0.05). There was significant difference in the positive rate of CRP WBCU N% in all patients at admission (P 0.05). There was no significant difference in the positive rate of CRP WBCU N% between all patients at discharge (P 0.05). There was significant difference in CRP between the abscess incision drainage group and non-abscess drainage group before treatment (P0.05), but there was no significant difference in CRP between the two groups after treatment (P0.05). Conclusion (1) CRP can be used as one of the sensitive indexes to reflect the course of odontogenic space infection.
【作者单位】：石河子大学医学院第一附属医院口腔科;
【基金】：石河子大学医学院第一附属医院院级科研项目(No.SS2010052)
【分类号】：R782.3

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