拔牙窝填塞Bio-oss人工骨对延期种植骨结合影响的组织学观察

发布时间：2018-09-01 10:41

【摘要】：目的:评价拔牙后牙槽窝内填塞Bio-oss人工骨对延期种植骨结合的影响,为临床提供实验依据。方法:全麻下拔除6只杂种犬双侧下颌第三、四前磨牙,随机选取两个拔牙窝作为实验组,牙槽窝内填塞Bio-oss人工骨粉并覆盖钛膜;另外两个拔牙窝不作任何处理作为对照组。术后3个在植入种植体,Golden's三色法观察种植体周围骨结合。结果:实验组及对照组种植体周围新骨均生成良好,实验组3个月可见Bio-oss颗粒;种植体植入术后3个月实验组的骨-种植体接触率及种植体周围骨面积均显著高于对照组,差异有统计学意义(P0.05)。种植体植入术后6个月实验组的骨-种植体接触率及种植体周围骨面积略高于对照组,但差异无统计学意义。结论:拔牙窝内填塞Bio-oss人工骨有利于延期种植骨结合。
[Abstract]:Objective: to evaluate the effect of Bio-oss artificial bone implantation in alveolar fossa after extraction on delayed implant bone bonding and to provide experimental evidence for clinical application. Methods: the third and fourth premolars of 6 mongrel dogs were extracted under general anesthesia. Two extraction nests were randomly selected as experimental group, the alveolar fossa was filled with Bio-oss artificial bone powder and covered with titanium membrane, and the other two extraction nests were not treated as control group. Bone binding around implants was observed by Goldens3 method after operation. Results: Bio-oss granules were found in the experimental group and the control group at 3 months after implantation, and the contact rate and the bone area around the implant in the experimental group were significantly higher than those in the control group at 3 months after implant implantation, and the bone contact rate and the bone area around the implant in the experimental group were significantly higher than those in the control group. The difference was statistically significant (P0.05). The osseous implant contact rate and bone area around implants in the experimental group were slightly higher than those in the control group 6 months after implant implantation, but the difference was not statistically significant. Conclusion: the implantation of Bio-oss artificial bone in the extraction fossa is beneficial to the delayed implantation of bone.
【作者单位】：大连医科大学动物实验中心;大连医科大学口腔医学院;
【基金】：国家自然科学基金课题(编号:81000669) 辽宁省自然科学基金(编号:201102045)
【分类号】：R783.6

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