不同再矿化制剂对酸蚀乳牙釉质影响的比较研究
发布时间：2018-10-15 12:38
【摘要】：目的观察再矿化制剂酪蛋白磷酸肽-无定形磷酸钙复合物(CPP-ACP)、含氟酪蛋白磷酸肽-无定形磷酸钙复合物(CPP-ACPF)、含氟磷酸三钙(TCP+F)和Duraphat保护漆对酸蚀乳牙釉质表面硬度和表面形态的影响。方法选取因滞留拔除的下颌乳中切牙制备离体牙釉质块(硬度值280~330 HV)试件50个,并随机分为对照组、CPP-ACP组、CPP-ACPF组、TCP+F组和Duraphat组。酸蚀处理所有试件(可口可乐,5次/d,5 min/次,共5 d),酸蚀完成后,5组试件分别涂布去离子水(对照组)和CPP-ACP、CPP-ACPF、TCP+F、Duraphat进行再矿化处理,随后继续酸蚀处理5 d。采用显微硬度法测量处理前后各组试件的表面硬度(显微硬度值),扫描电子显微镜(扫描电镜)观察牙釉质表面形态的变化。结果酸蚀处理前5组试件显微硬度值的差异无统计学意义(P0.05);酸蚀处理后各组试件的显微硬度值均显著低于酸蚀处理前(P0.05),但各组间比较差异无统计学意义(P0.05);分组处理继续酸蚀5 d后,CPP-ACP组、CPP-ACPF组、TCP+F组和Duraphat组试件的显微硬度值均显著高于对照组(P0.05),但4组间的差异无统计学意义(P0.05)。扫描电镜观察发现,分组处理继续酸蚀5 d后,除对照组试件外,其余4组牙釉质块试件均可见矿物质沉积。结论再矿化制剂CPP-ACP、CPP-ACPF、TCP+F和Duraphat均能有效抑制酸蚀乳牙釉质的持续脱矿。
[Abstract]:Objective to observe the surface hardness of casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP), fluorine-containing casein phosphate-amorphous calcium phosphate complex (CPP-ACPF), tricalcium phosphate (TCP F) and Duraphat protective paint on the enamel surface of acid-etched milk. The effect of surface morphology. Methods 50 specimens of enamel mass (hardness of 280 ~ 330 HV) were prepared from the central incisor of mandibular milk after extraction and were randomly divided into three groups: control group, CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group. All the specimens (Coca-Cola, 5 times / dl, 5 min/) were treated with deionized water (control group) and CPP-ACP,CPP-ACPF,TCP FU Duraphat for 5 d), after the etching was completed, and then the treatment was continued for 5 days. The surface hardness (microhardness) of each group of specimens before and after treatment was measured by microhardness method, and the changes of enamel surface morphology were observed by scanning electron microscope (SEM). Results there was no significant difference in microhardness values between the five groups before acid etching treatment (P0.05), and the microhardness values of each group after acid etching treatment were significantly lower than those before acid etching treatment (P0.05), but there was no significant difference among the groups (P0.05). After continuous etching for 5 days, the microhardness of CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group were significantly higher than that of control group (P0.05), but there was no significant difference among the four groups (P0.05). Scanning electron microscopy (SEM) showed that mineral deposits were observed in the enamel samples of the other 4 groups except the control group after 5 days of treatment. Conclusion both CPP-ACP,CPP-ACPF,TCP F and Duraphat can effectively inhibit the continuous demineralization of enamel.
【作者单位】： 口腔疾病与生物医学重庆市重点实验室重庆医科大学附属口腔医院儿童口腔科;
【基金】：重庆市卫生局2012年医学科研计划项目(2012-2-126) 重庆市教委科学技术研究项目(kj120329)~~
【分类号】：R781.2
本文编号：2272580
[Abstract]:Objective to observe the surface hardness of casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP), fluorine-containing casein phosphate-amorphous calcium phosphate complex (CPP-ACPF), tricalcium phosphate (TCP F) and Duraphat protective paint on the enamel surface of acid-etched milk. The effect of surface morphology. Methods 50 specimens of enamel mass (hardness of 280 ~ 330 HV) were prepared from the central incisor of mandibular milk after extraction and were randomly divided into three groups: control group, CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group. All the specimens (Coca-Cola, 5 times / dl, 5 min/) were treated with deionized water (control group) and CPP-ACP,CPP-ACPF,TCP FU Duraphat for 5 d), after the etching was completed, and then the treatment was continued for 5 days. The surface hardness (microhardness) of each group of specimens before and after treatment was measured by microhardness method, and the changes of enamel surface morphology were observed by scanning electron microscope (SEM). Results there was no significant difference in microhardness values between the five groups before acid etching treatment (P0.05), and the microhardness values of each group after acid etching treatment were significantly lower than those before acid etching treatment (P0.05), but there was no significant difference among the groups (P0.05). After continuous etching for 5 days, the microhardness of CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group were significantly higher than that of control group (P0.05), but there was no significant difference among the four groups (P0.05). Scanning electron microscopy (SEM) showed that mineral deposits were observed in the enamel samples of the other 4 groups except the control group after 5 days of treatment. Conclusion both CPP-ACP,CPP-ACPF,TCP F and Duraphat can effectively inhibit the continuous demineralization of enamel.
【作者单位】： 口腔疾病与生物医学重庆市重点实验室重庆医科大学附属口腔医院儿童口腔科;
【基金】：重庆市卫生局2012年医学科研计划项目(2012-2-126) 重庆市教委科学技术研究项目(kj120329)~~
【分类号】：R781.2
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