颧骨种植体支抗后牵引猴上颌骨骨缝反应的组织学定量研究

发布时间：2018-10-17 21:47

【摘要】：目的研究种植体支抗后牵引矫形力作用下上颌骨相关骨缝改建特点,探讨后牵引抑制上颌骨生长的作用机制。方法选用青春生长发育期的雄性恒河猴4只,随机分为3组(1.5月组1只、3月组2只和对照组1只)。实验组在其颧骨体部植入微钛板种植体,上颌佩戴全牙弓夹板,以单侧150g力的Ni-Ti螺旋拉簧连接上述部分,方向与平面平行,建立了颧骨种植体支抗后牵引上颌骨动物模型。采用组织学苏木精-伊红染色及计算机组织形态测定技术,定量分析骨缝反应的变化情况。结果骨缝宽度:在后牵引力作用下,颧颌缝、翼腭缝、横腭缝和颧颞缝骨缝宽度减小;腭中缝、额颌缝、蝶颧缝和颧额缝骨缝宽度增大。其中,额颌缝、蝶颧缝3月组增加较为明显,1.5月组与对照组相比差异无统计学意义;而颧颞缝、翼腭缝1.5月组减小较为明显,但与3月组比较差异无统计学意义。细胞密度:在后牵引力作用下,1.5月组各骨缝细胞密度均增大,随着牵引时间延长,颧颌缝、翼腭缝、横腭缝和颧颞缝细胞密度减小,呈现出压缩效应;腭中缝、额颌缝、蝶颧缝和颧额缝细胞密度增大,呈现出牵张效应,结果与骨缝宽度变化一致。但是随着牵引时间的进一步延长,骨缝的细胞密度变化略有差异。颧颌缝、翼腭缝、腭中缝和额颌缝1.5月组与3月组相比差异无统计学意义。结论后牵引力作用下,上颌骨有向后压缩并伴顺时针旋转趋势,颧骨作为支抗承载骨也有一定的旋转趋势。与正中矢状面有一定夹角的后牵引力对上颌腭中缝有横向扩弓的效应。
[Abstract]:Objective to study the remodeling characteristics of maxillary associated suture under orthopedic force of implant Anchorage, and to explore the mechanism of posterior traction on the inhibition of maxillary growth. Methods four male rhesus monkeys were randomly divided into 3 groups (1. 5 month group, 2 3 months group and 1 control group). In the experimental group, microtitanium plate implants were implanted in the zygomatic body and the maxillary arch splint was worn. The animal model of maxillary traction was established by using a Ni-Ti helical pull spring with a unilateral force of 150g. The direction was parallel to the plane. Histopathological hematoxylin-eosin staining and computer histomorphometry were used to quantitatively analyze the changes of bone suture reaction. Results width of suture: the width of zygomatigomaxillary suture, pterygopalatine suture, transverse palatine suture and zygomaticotemporal suture decreased, and the width of palatine middle suture, frontomaxillary suture, sphenozygomatic suture and zygomatic frontal suture increased. Among them, the frontal and maxillary suture and sphenozygomatic suture increased significantly in 3 months group, but there was no significant difference between 1.5 month group and control group, but the decrease of zygomaticotemporal suture and pterygopalatine suture 1.5 month group was more obvious, but there was no significant difference compared with 3 month group. Cell density: under the action of posterior traction, the cell density of bone suture increased in 1.5 months group. With the extension of traction time, the cell density of zygomatigomaxillary suture, pterygopalatine suture, transverse palatine suture and zygomatic-zygomatic suture decreased. The density of sphenozygomatic suture and zygomatic frontal suture increased, showing the effect of distraction, and the results were consistent with the width of bone suture. However, with the further extension of traction time, the cell density of bone suture changed slightly. There was no significant difference in zygomatigomaxillary suture, pterygopalatine suture, palatine suture and frontomaxillary suture 1.5 months compared with 3 months group. Conclusion the maxillary bone has the tendency of backward compression and clockwise rotation under the action of posterior traction, and the zygomatic bone as the Anchorage bearing bone has a certain tendency of rotation. The posterior traction with a certain angle to the median sagittal plane has the effect of transverse expansion of the maxillary palatine suture.
【作者单位】：四川省自贡市第四人民医院口腔科;昆明医科大学附属口腔医院正畸科;
【基金】：国家自然科学基金资助项目(No.81060089)
【分类号】：R783.5

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