牙齿脱敏剂对釉质再矿化的体外研究

发布时间：2018-11-03 21:10

【摘要】：目的:通过体外实验的方法对奥敏清牙齿脱敏剂、含氟牙膏对脱矿釉质再矿化的作用进行比较。方法:63颗离体牙人工脱矿后随机分为3组,分别使用奥敏清牙齿脱敏剂、1.1 g/L含氟牙膏、去离子水进行再矿化处理8 d,激光扫描共聚焦显微镜(CLSM)观察釉质切片并定量分析、扫描电镜(SEM)观察釉质表面形态。结果:CLSM数据显示奥敏清处理组及含氟牙膏处理组荧光面积(A)分别为(3.19±0.19)×10~4、(3.61±0.26)×10~4μm~2,总荧光量(TF)分别为(0.61±0.09)×106、(0.89±0.15)×106,平均荧光量(AF)分别为(18.98±1.56)、(24.65±2.39),均低于空白对照组[A=(4.89±0.24)×10~4μm2,TF=(1.78±0.21)×10~6,AF=36.29±2.57](P0.01);奥敏清处理组的各参数值低于含氟牙膏处理组(P0.05)。SEM观察奥敏清处理组釉质表面形态最平整,含氟牙膏处理组次之,空白对照组最为粗糙。结论:本实验条件下,奥敏清牙齿脱敏剂及1.1 g/L含氟牙膏对脱矿釉质均有再矿化作用,奥敏清牙齿脱敏剂的作用更强。
[Abstract]:Aim: to compare the effect of Omin Qing tooth desensitizer and fluoride toothpaste on demineralization of enamel in vitro. Methods: 63 isolated teeth were randomly divided into 3 groups after artificial demineralization. They were treated with Aomin Qing tooth desensitizer, 1.1 g / L fluoride toothpaste and deionized water for 8 days, respectively. Laser scanning confocal microscope (CLSM) was used to observe the enamel sections and quantitative analysis was made. The surface morphology of enamel was observed by scanning electron microscope (SEM). Results: CLSM data showed that the fluorescence area (A) of Aomin Qing treatment group and fluoride toothpaste treatment group were (3.19 卤0.19) 脳 10 ~ (4) 渭 m ~ (-2) and (3.61 卤0.26) 脳 10 ~ (4) 渭 m ~ (-2) respectively. The total fluorescence (TF) was (0.61 卤0.09) 脳 10 ~ (-6), respectively. (0. 89 卤0. 15) 脳 10 ~ (6) 脳 10 ~ (6) 脳 10 ~ (6) (AF), respectively (18.98 卤1.56), (, 24.65 卤2.39), which were lower than those in the blank control group [A = (4.89 卤0.24) 脳 10 ~ (4) 脳 10 ~ (4) 渭 m ~ (2) TF = (1.78 卤0.21) 脳 10 ~ (6) (AF) = (36.29 卤2.57) (P < 0.01); The parameters of Aomin Qing treatment group were lower than that of fluoride toothpaste treatment group (P0.05). SEM observation of the surface morphology of enamel was the most smooth, fluoride toothpaste treatment group was the second, blank control group was the roughest. Conclusion: in this experiment, the desensitizer and 1.1 g / L fluoride toothpaste have remineralization effect on demineralized enamel, and the effect of the desensitizer is stronger.
【作者单位】：南京医科大学附属南京儿童医院;
【基金】：江苏省预防医学科研基金资助项目(编号:Y2013003)
【分类号】：R781.1

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