异种脱细胞修复膜引导角化牙龈生长的初步研究

发布时间：2018-11-14 14:06

【摘要】：目的观察异种脱细胞真皮基质(ADM)修复膜在引导角化牙龈组织生长的组织学表现。方法选取中山市人民医院口腔种植科2016年上前牙单牙缺失种植病例6例,随机分成2组。其中3例为实验组:上前牙区拔除单颗患牙后,即刻植入Ankylos?种植体,在种植体与拔牙窝骨板之间植入人工骨替代材料后,无松解拔牙创周围软组织,在暴露创口覆盖两层与暴露创口外形一致的异种脱细胞真皮基质修复膜,非吸收缝线褥式缝合固定,生物膜暴露在口腔环境;另3例为对照组:常规延期种植,上前牙单牙缺失,无组织引导生长,直接拉拢缝合。术后10 d拆线。所有病例均4个月后在种植体平台环切取得软组织,常规组织学切片,显微镜下观察。结果实验组在引导生成的牙龈软组织切片显示新生软组织有类似角化牙龈的结构。但与对照组在组织学结构有差异。结论双层异种脱细胞真皮基质修复膜可以引导角化牙龈生长。
[Abstract]:Objective to observe the histological features of xenogeneic acellular dermal matrix (ADM) repair membrane in guiding keratinized gingival tissue growth. Methods A total of 6 cases of missing anterior teeth in the Department of Oral Implant, Zhongshan people's Hospital in 2016 were randomly divided into 2 groups. Three of them were in experimental group: Ankylos? was implanted immediately after the extraction of a single affected tooth in the maxillary region. Implants: after implantation of artificial bone substitute material between implant and extraction fossa bone plate, there is no release of soft tissue around tooth extraction, and two layers of xenogeneic acellular dermal matrix repair membrane with the same shape as exposed wound are covered in exposed wound. Non-absorbent suture mattress suture fixation biofilm exposed to oral environment; The other 3 cases were treated as control group: conventional delayed implantation, single tooth loss, unorganized growth and direct closure and suture. The thread was removed 10 days after operation. Soft tissue was obtained after 4 months of circumcision of the implant platform, and was observed under microscope. Results the soft tissue sections of the experimental group showed that the new soft tissue had a structure similar to keratinized gingiva. But there was a difference in histological structure between the control group and the control group. Conclusion double layer acellular dermal matrix repair membrane can induce keratinized gingival growth.
【作者单位】：广东省中山市人民医院口腔种植科;
【分类号】：R783.6

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