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替牙期单侧完全性唇腭裂患者鼻上颌复合体对称性研究

发布时间:2018-12-26 14:44
【摘要】:目的:对替牙期单侧完全性唇腭裂(Unilateral complete cleft lip and palate,UCLP)患者的锥形束CT(Cone Beam Computed Tomography,CBCT)影像进行对比分析,研究替牙期UCLP患者鼻上颌复合体的对称性,为其颅面形态的研究以及临床治疗提供更好的理论依据。方法:选择20例替牙期UCLP患者作为UCLP组,20例替牙期非唇腭裂患者作为对照组。所有研究对象进行锥形束CT扫描,获得CBCT影像,导入MIMICS 17.0软件进行三维重建。在三维图像上确定LPA点(梨状孔最外侧缘点)、INM点(鼻额缝最下点)、Maz点(颧牙槽嵴点)、SPM点(上颌第一磨牙牙槽缘点)、SPC点(上颌尖牙牙槽缘点)、SPr点(上颌中切牙牙槽缘点)等34个标志点,并建立三维坐标系,用软件自带的测量工具对两组患者鼻上颌复合体的各项线距进行测量。用SPSS 22.0统计软件包对测量结果进行统计和分析,比较UCLP患者裂隙侧与非裂隙侧鼻上颌复合体的对称性,分析其裂隙侧与非裂隙侧的生长差异;比较对照组患者鼻上颌复合体的对称性。结果:1.鼻上颌复合体水平向对称性UCLP组患者裂隙侧LPA点处上颌骨的宽度、SPr点处单侧牙弓宽度大于非裂隙侧,INM点处鼻上颌复合体的宽度、SPC点处单侧牙弓宽度小于非裂隙侧,存在统计学差异(P0.05)。对照组左右侧各测量值之间无统计学差异(P0.05)。2.鼻上颌复合体矢状向对称性UCLP组患者裂隙侧的LPA点、Maz点、SPr点处上颌骨的矢状向发育差于非裂隙侧,SPM、SPC点位置相对于非裂隙侧偏前,存在统计学差异(P0.05)。对照组左右侧各测量值之间无统计学差异(P0.05)。2.鼻上颌复合体垂直向对称性UCLP组患者裂隙侧的LPA点处上颌骨高度、INM点处鼻上颌复合体的高度、Maz点处上颌骨的高度大于非裂隙侧,SPC点、SPr点处上颌骨高度小于非裂隙侧,存在明显统计学差异(P0.05)。对照组左右侧各测量值之间无统计学差异(P0.05)。结论:1、替牙期UCLP患者鼻上颌复合体存在不对称性,且不对称主要集中在鼻腔和牙槽骨处。2、替牙期非唇腭裂患者鼻上颌复合体无明显不对称。
[Abstract]:Objective: to study the symmetry of nasal and maxillary complex in patients with unilateral cleft lip and palate (Unilateral complete cleft lip and palate,UCLP) by comparing and analyzing the CT (Cone Beam Computed Tomography,CBCT images of conical bundle in patients with unilateral cleft lip and palate. To provide a better theoretical basis for the study of craniofacial morphology and clinical treatment. Methods: 20 patients with UCLP were selected as UCLP group and 20 patients with non-cleft lip and palate as control group. All the subjects were scanned by conical beam CT, and CBCT images were obtained and imported into MIMICS 17.0 software for 3D reconstruction. The LPA point (), INM point at the most lateral edge of piriform foramen) (), Maz point at the lowest point of the nasal suture (), SPM point at the zygomatic alveolar ridge point) (), SPC point at the alveolar edge point of the maxillary first molar) was determined on 3D images. 34 mark points such as SPr point (incisor point) and three dimensional coordinate system were set up to measure the distance of each line of nasal maxillary complex between two groups of patients by using the software's own measuring tool. The measurement results were analyzed by SPSS 22.0 software package. The symmetry of the nasal maxillary complex between the fissured side and the non-fissured side of UCLP was compared, and the growth difference between the fissured side and the non-fissured side was analyzed. The symmetry of nasal maxillary complex in control group was compared. Results: 1. In UCLP group, the width of maxillary bone at the LPA point of the fissure side, the width of the unilateral arch at the SPr point was larger than that of the non-fissured side, the width of the nasal maxillary complex at the INM point and the width of the unilateral arch at the SPC point was smaller than that at the non-fissured side. There was statistical difference (P0.05). There was no statistical difference between the left and right side of the control group (P0.05). In the sagittal symmetry UCLP group, the sagittal development of the maxilla at the LPA, Maz and SPr points of the maxillary complex was worse than that of the non-fissured side, and the position of the SPM,SPC point was significantly different from that of the non-fissured side (P0.05). There was no statistical difference between the left and right side of the control group (P0.05). In the UCLP group, the maxillary height at the LPA point at the fissure side, the maxillary complex height at the INM point, the maxillary height at the Maz point were higher than those at the non-fissured side, the maxillary height at the SPC point and the SPr point were lower than those at the non-fissured side. There was significant statistical difference (P0.05). There was no statistical difference between the left and right side of the control group (P0.05). Conclusion: 1. There is asymmetry in nasal maxillary complex in patients with UCLP, and the asymmetry is mainly in nasal cavity and alveolar bone. 2. There is no obvious asymmetry in nasal maxillary complex in patients with non-cleft lip and palate.
【学位授予单位】:青岛大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R782.2

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