酪蛋白磷酸肽-非结晶型磷酸钙溶液预防牙釉质脱矿的实验研究

发布时间：2019-01-02 15:08

【摘要】：目的观察GC护牙素[酪蛋白磷酸肽一非结晶型磷酸钙(CPP-ACP)溶液]预防脱矿液对牙釉质脱矿的效果。方法选取68个因正畸需要拔除的未患龋的前磨牙,均未见牙体表面缺损,彻底清洗后切割成釉质面,打磨成平滑面,保留釉质窗口面,随机分成4组,分别置于0.2%NaF、2%NaF、CPP-ACP、蒸馏水中浸泡7 d,置于脱矿夜中浸泡7 d。进行扫描电镜照射,观察釉质层变化,同时采用电子探针检测仪检测脱矿后釉质层硬组织钙、磷、镁3种元素的分布状况,并进行统计学分析。结果 0.2%NaF、2%NaF、CPP-ACP溶液组牙釉质脱矿率均低于蒸馏水组,且釉质层中钙、磷的含量明显高于蒸馏水组,而镁元素的含量4组无统计学差异,说明0.2%NaF、2%NaF、CPP-ACP均对预防牙釉质脱矿有一定的保护作用。结论 5%CPP-ACP是一种预防牙釉质脱矿的安全有效的措施,其作用与0.2%NaF组相似。
[Abstract]:Objective to observe the effect of GC dentin [casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) solution] on enamel demineralization. Methods Sixty-eight premolars without caries were selected for orthodontic extraction. No tooth surface defect was found. After thorough cleaning, enamel surface was cut into smooth surface, glazed window surface was retained, and randomly divided into 4 groups, placed in 0.2 NAF, respectively. (2) NaFU CPP-ACP, soaked in distilled water for 7 days and immersed in demineralized night for 7 days. The changes of enamel layer were observed by scanning electron microscope (SEM), and the distribution of calcium, phosphorus and magnesium in hard tissue of enamel layer after demineralization was detected by electron probe detector, and the distribution of calcium, phosphorus and magnesium in enamel layer after demineralization was analyzed statistically. Results the enamel demineralization rate was lower in the NaFU CPP-ACP solution group than in the distilled water group, and the contents of calcium and phosphorus in the enamel layer were significantly higher than those in the distilled water group, but there was no statistical difference in the magnesium content in the four groups, indicating that 0.2NaF. CPP-ACP can protect enamel from demineralization to some extent. Conclusion 5%CPP-ACP is a safe and effective measure to prevent enamel demineralization and its effect is similar to that of 0.2%NaF group.
【作者单位】：广州市妇女儿童医疗中心口腔科;
【基金】：广州市医药卫生科技项目(201102A213041)
【分类号】：R783.5

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