西吡氯铵与聚维酮碘含漱液对口腔假丝酵母菌属感染的疗效

发布时间：2019-07-17 17:08

【摘要】：目的探讨西吡氯铵与聚维酮碘含漱液对口腔假丝酵母菌属感染患者的临床治疗效果。方法选取2011年1月-2012年12月100例口腔假丝酵母菌属感染患者为研究对象,将其按照随机数字法分为对照组和观察组,对照组给予聚维酮碘含漱液治疗,观察组给予西吡氯铵含漱液治疗,均治疗两周,观察两组的临床治疗效果,所有检测数据采用SPSS19.0软件进行统计分析。结果临床治疗总有效率观察组为96.0%、对照组为74.0%,两组总有效率比较差异有统计学意义(P0.05);对照组和观察组治疗前真菌镜检阳性率分别为70.0%、72.0%,治疗后阳性率分别为40.0%、28.0%,两组比较差异有统计学意义(P0.05)。结论临床中口腔假丝酵母菌属感染患者应用西吡氯铵含漱液的治疗效果明显优于聚维酮碘含漱液的治疗效果,能够有效的缓解患者的临床症状,并对真菌的清除效果更强,治疗安全性高,值得临床应用与推广。
[Abstract]:Objective to investigate the clinical effect of cimidonium chloride and povidone iodine gargle on patients with oral candida infection. Methods from January 2011 to December 2012, 100 patients with oral candida infection were randomly divided into control group and observation group. The control group was treated with povidone iodine gargle and the observation group was treated with cipyrilonium chloride gargle for two weeks. The clinical therapeutic effects of the two groups were observed. All the detection data were statistically analyzed by SPSS19.0 software. Results the total effective rate of clinical treatment was 96.0% in the observation group and 74.0% in the control group, and there was significant difference between the two groups (P 0.05). The positive rates of fungal microscopic examination before treatment and in the observation group were 70.0% and 72.0% respectively, and the positive rates after treatment were 40.0% and 28.0% respectively, and there was significant difference between the two groups (P 0.05). Conclusion in clinical treatment of oral candida infection, the therapeutic effect of cipyridinium chloride gargle is obviously better than that of povidone iodine gargle, which can effectively alleviate the clinical symptoms of patients, and has stronger scavenging effect on fungi and higher safety of treatment, which is worthy of clinical application and popularization.
【作者单位】：浙江省天台县中医院口腔科;浙江省天台县中医院药剂科;
【基金】：浙江省卫生厅医药卫生计划基金项目(2011KYB003)
【分类号】：R781.5

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