浙江省衢州市不同时期流行性腮腺炎发病特征比较

发布时间：2018-04-25 08:46

本文选题：流行性腮腺炎 + 流行病学特征　；参考：《中国疫苗和免疫》2017年06期

【摘要】：目的比较浙江省衢州市2004-2016年流行性腮腺炎(流腮)发病特征变化。方法将衢州市2004-2016年的流腮疫情分成扩大免疫规划(EPI)前期(2004-2006年)、EPI期(2007-2010年)及含流腮成分疫苗(Mu CV)强化免疫(SIA)期(2011-2016年),运用描述性流行病学方法比较三个时期流腮发病特征的变化。结果三个时期流腮年均报告发病率分别为45.24/10万、41.01/10万和12.54/10万(趋势x2=2 290.23,P=0.00)。EPI前期和EPI期均有4-6月和11-12月两个发病高峰,而SIA期发病高峰不明显。三个时期学生的发病构成比分别为73.21%、67.59%和58.28%;男女性别发病比分别为1.55∶1、1.66∶1和1.44∶1;4-14岁组发病率分别为217.98/10万、213.42/10万和59.73/10万。三个时期出生队列流腮的高发年龄段分别为5岁组、3岁组和4岁组。EPI前期和EPI期共报告流腮突发公共卫生事件29起,23起发生在小学和22起发生在3-6月,SIA期无突发事件报告。结论衢州市引入Mu CV特别是2剂次接种使流腮发病率迅速下降;建议推行儿童2剂次Mu CV常规免疫程序。
[Abstract]:Objective to compare the characteristics of mumps (gills) from 2004 to 2016 in Quzhou, Zhejiang province. Methods the gills epidemic in Quzhou from 2004 to 2016 were divided into two groups: EPI (2004-2006) and MU (CVC) (2011-2016). The characteristics of gills in the three phases were compared by descriptive epidemiological method. Results the average annual reported incidence of gills in the three periods was 45.24 / 100 000 and 12.54 / 100 000 respectively (trend x 2290.23). There were two peaks in pre-EPI and EPI, but the peak in SIA was not obvious. The incidence ratio of male to female was 1.55: 1: 1.66: 1 and 1.44: 1 to 14 years old, respectively. The incidence rates were 21798 / 100 000 and 59.73% / 100 000, respectively, for the students aged from 4 to 14 years of age, 73.21%, 67.59% and 58.28%, respectively, and the incidence rates were 21798 / 100 000 and 59.73% / 100 000, respectively. The high incidence age of Gill was 5 years old group (3 years old) and 4 year old group (4 years old). A total of 29 cases (23 / 23) occurred in primary school and 22 cases occurred in March / June (March / June). Conclusion introduction of Mu CV especially two doses of inoculation in Quzhou City can decrease the incidence of gills rapidly and it is suggested to carry out routine immunization program of 2 doses of Mu CV in children.
【作者单位】：衢州市疾病预防控制中心;
【基金】：浙江省疾病预防控制中心重点实验室开放课题(编号:2016-07) 浙江省预防医学会免疫规划软课题(编号:2017YF03)
【分类号】：R181.3;R512.1

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