天津市宁河县适龄儿童含麻疹成分疫苗免疫后抗体检测结果分析

发布时间：2018-04-30 22:07

本文选题：麻疹 + 免疫　；参考：《中国妇幼保健》2014年23期

【摘要】：目的:对宁河县适龄儿童含麻疹成分疫苗免疫后抗体阳性率进行监测分析,为今后的免疫服务和制定相关政策提供科学依据。方法:随机选取部分城镇地区和农村地区接种过含麻疹成分疫苗的适龄儿童,对其家长进行告知,采集儿童指尖血,ELISA法检测麻疹抗体IgG。结果:共检测1 081例适龄儿童的麻疹抗体IgG,1 070例阳性,阳性率98.98%。男性596例,589例阳性,阳性率98.82%;女性485例,481例阳性,阳性率99.18%。9月龄~组阳性率为98.65%,24月龄~组为99.22%。接种1、2、3剂次的阳性率分别为98.22%、99.03%和99.70%。城镇地区阳性率98.36%,农村地区为99.30%。结论:宁河县适龄儿童含麻疹成分疫苗免疫后抗体阳性率高,不同性别、不同年龄组、不同接种剂次、不同地区的阳性率差异无统计学意义;个别儿童接种疫苗后未能产生抗体,存在免疫失败现象。
[Abstract]:Objective: to monitor and analyze the antibody positive rate of children with measles vaccine in Ninghe county, so as to provide scientific basis for future immunization service and related policies. Methods: children who had been vaccinated with measles vaccine in some urban and rural areas were randomly selected, and their parents were informed, and their children's fingertip blood samples were collected to detect the measles antibody IgG by Elisa. Results: a total of 1081 cases of children of right age were tested for measles antibody IgG in 1070 cases, and the positive rate was 98.98 8%. 596 cases of male 589 cases were positive, the positive rate was 98.82%, and 485 cases of female were positive in 481 cases, the positive rate of 99.18.9 months group was 98.65% and the positive rate of 24-month group was 99.22%. The positive rates of 3 doses inoculation were 98.22% and 99.70%, respectively. The positive rate was 98.36 in urban areas and 99.30 in rural areas. Conclusion: the positive rate of antibody was high in children of Ninghe county after immunization with measles vaccine. There was no significant difference in the positive rate between different age groups, different age groups, different inoculants and different areas. Some children failed to produce antibodies after inoculation, which resulted in the failure of immunization.
【作者单位】：天津市宁河县疾病预防控制中心;天津市宁河县芦台医院;天津市宁河县东棘坨镇卫生院;天津市宁河县廉庄乡卫生院;
【分类号】：R186

【相似文献】