吉林省扶余县农村居民丙型肝炎流行状况的研究

发布时间：2018-06-18 14:33

本文选题：丙型肝炎 + 流行　；参考：《吉林大学》2010年硕士论文

【摘要】： 本次调查研究对吉林省扶余县更新乡愿意接受调查的10个村中采取统一的调查表,以面访的形式对参加对象进行问卷调查。并于问卷当天进行血样采集,检查肝功能、丙肝抗体、乙肝表面抗原,丙肝抗体阳性者行HCVRNA的检查。在我们下乡进行调查之前,与当地乡政府、疾病控制中心取得联系,并达成合作,由他们提前做好通知工作,做到挨家挨户上门通知,说明我们本次调查的目的和意义,鼓励更多的人参加本次调查。本次调查的内容主要包括调查对象基本信息,家庭人口、吸烟史,饮酒史,既往肝炎病史、糖尿病病史、家庭成员肝病病史、输血史、献血史、安纳咖注射史、周围人安纳咖注射史、修牙史、纹眉史、扎耳洞史、既往丙肝诊治史等。我们发现有安纳咖注射史的是HCV感染最强的相关因素(OR=11.71),其次是年龄、肝炎史、吸烟、文化程度、周围人安纳咖注射史也是HCV感染的独立相关因素,而且我们发现调查地区的人群对丙肝的认知率低,就诊率低,治疗率低,而感染率却很高,存在极大的隐患,应该引起我们全社会的关注。结论：扶余县更新乡HCV粗感染率为49.40%,约是全国HCV感染的15.44倍,是我国丙型肝炎高发区。HCV感染与年龄、吸烟史、文化程度、肝炎史、是否有安纳咖注射史、周围人安纳咖注射史有关。安纳咖注射人群是扶余县更新乡农村HCV感染的高危人群,是当地HCV感染的主要传播途径扶余县更新乡丙肝感染率高、检测率低、知晓率低、治疗率低、治疗效果差。扶余县更新乡面临丙型肝炎高感染率和低发现率、低治疗率的重大挑战,应采取及时有效的策略控制发病、规范治疗,减轻当地经济和社会负担。
[Abstract]:In this investigation, 10 villages in Fuyu County, Jilin Province, were surveyed with a unified questionnaire, and the participants were surveyed in the form of an interview. Blood samples were collected on the same day of the questionnaire to examine the liver function, hepatitis C antibody, hepatitis B surface antigen and hepatitis C antibody positive for HCV RNA. Before we go to the countryside for investigation, contact and cooperate with the local township government and the Centers for Disease Control and Control, so that they can do a good job of notification in advance, so that we can go door-to-door notice. This explains the purpose and significance of our investigation. Encourage more people to participate in the survey. The contents of this survey mainly include basic information of the subjects, family population, smoking history, drinking history, past history of hepatitis, history of diabetes, history of liver disease among family members, history of blood transfusion, history of blood donation, history of Anakah injection. Anakah injection history, tooth repair history, eyebrow stripe history, ear hole history, previous history of diagnosis and treatment of hepatitis C, etc. We found that the most important factor associated with HCV infection was the history of Anakah injection, followed by age, history of hepatitis, smoking, education, and the history of injection of Anakana around us, which were also independent related factors of HCV infection. Moreover, we found that the people in the investigation area have low cognition rate, low visiting rate, low treatment rate, but the infection rate is very high, there are great hidden dangers, so we should pay attention to the whole society. Conclusion: the crude infection rate of HCV in Yuexin Township of Fuyu County is 49.400.It is 15.44 times higher than that in the whole country. It is the infection rate and age, smoking history, education level, history of hepatitis and whether or not there is the history of Ana injection in the high incidence area of hepatitis C in China. The history of the injection of Anakah around people. Anaqa injection population is a high risk group of HCV infection in rural areas of Fuyu County. It is the main way of transmission of HCV infection in Fuyu County. The infection rate of hepatitis C is high, the detection rate is low, the awareness rate is low, and the therapeutic effect is poor. Yuexin Township of Fuyu County is faced with the great challenge of high infection rate, low detection rate and low treatment rate of hepatitis C. We should take timely and effective strategies to control the disease, standardize the treatment and lighten the local economic and social burden.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R512.63;R181.3

【参考文献】