喉罩与气管插管全麻用于非小细胞肺癌根治术的临床观察

发布时间：2018-01-23 22:45

本文关键词： 喉罩气管插管非小细胞肺癌炎症反应生存质量　出处：《实用医学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的:评估喉罩全麻胸腔镜手术治疗非小细胞肺癌的可行性及安全性。方法:回顾性分析我院2016年3-8月间40例非小细胞肺癌根治术患者的临床资料,其中喉罩组20例,气管插管组20例,比较两组患者术后恢复情况、全身炎症反应和术后生存质量等指标。结果:患者均顺利完成手术,无手术死亡病例,两组在手术时间、最低氧饱和度、最高呼末二氧化碳分压、术野和麻醉满意度、失血量方面无明显差异(P0.05)。喉罩组患者术后进食时间、抗生素使用时间、术后住院时间均短于气管插管组;喉罩组手术前后白细胞、中性粒细胞百分比和超敏C反应蛋白升高程度均低于气管插管组;喉罩组患者在术后生理状况、功能状况及生存质量总分等方面高于气管插管组,两组对比有显著差异(P0.05)。结论:喉罩全麻胸腔镜手术治疗非小细胞肺癌具有良好的可操作性和安全性,同时在降低全身炎症反应、加快术后康复、提高患者术后生存质量方面具有一定的优越性。
[Abstract]:Objective: to evaluate the feasibility and safety of thoracoscopic surgery under laryngeal mask general anesthesia in the treatment of non-small cell lung cancer (NSCLC). The clinical data of 40 patients with non-small cell lung cancer undergoing radical mastectomy between 2016 and August were retrospectively analyzed. There were 20 cases in laryngeal mask group and 20 cases in tracheal intubation group. The postoperative recovery, systemic inflammatory reaction and postoperative quality of life were compared between the two groups. There was no significant difference between the two groups in the operation time, the lowest oxygen saturation, the highest end-call partial pressure of carbon dioxide, the satisfaction of operation field and anesthesia, and the amount of blood loss (P 0.05). The antibiotic use time and postoperative hospitalization time were shorter than those in tracheal intubation group. The percentage of leukocytes, neutrophils and hypersensitive C-reactive protein in laryngeal mask group were lower than those in tracheal intubation group before and after laryngeal mask operation. The patients in laryngeal mask group were higher than those in tracheal intubation group in terms of postoperative physiological status, functional status and total score of quality of life. Conclusion: thoracoscopic surgery under laryngeal mask general anesthesia has good operability and safety in the treatment of non-small cell lung cancer. At the same time, it can reduce systemic inflammatory reaction and accelerate postoperative rehabilitation. There are some advantages in improving the quality of life after operation.
【作者单位】：南方医科大学南方医院胸外科;南方医科大学南方医院麻醉科;
【分类号】：R734.2
【正文快照】： 非小细胞肺癌是世界各国最常见的呼吸道恶性肿瘤,目前胸腔镜手术已成为治疗非小细胞肺癌的主要手术方法,其中麻醉是胸腔镜手术的重要组成部分[1-2]。因此,如何获得稳定的麻醉效果,降低麻醉引起的创伤和危害,是目前亟需解决的问题。近年来,喉罩全麻应用于胸腔镜手术日趋频繁,

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