不同剂量右美托咪定在胃肠道肿瘤患者腹腔热灌注化疗围术期中的效果

发布时间：2019-07-11 15:21

【摘要】：目的:探讨在胃肠道肿瘤患者实施腹腔热灌注化疗(IPHC)围术期中应用右美托咪定的临床效果。方法:选择2014年3月至2015年6月在本院接受IPHC的60例胃肠道肿瘤患者作为观察对象,按照围术期中右美托咪定应用剂量的不同将患者分为对照组(低剂量0.2μg/kg,n=30)、观察组(高剂量0.5μg/kg,n=30),对比分析两组患者术中生命体征变化、麻醉效果等。结果:观察组麻醉优良率为100%,明显高于对照组的90.00%,患者术中生命体征更为平稳,术后恢复更快,组间差异比较存在统计学意义(P0.05)。结论:在胃肠道肿瘤患者接受IPHC的围术期使用不同剂量右美托咪定,可取得良好的麻醉、镇静效果,且高剂量效果更佳。
[Abstract]:Objective: to investigate the clinical effect of dexmetomide during perioperative period of intraperitoneal hyperthermic infusion chemotherapy (IPHC) in patients with gastrointestinal tumors. Methods: from March 2014 to June 2015, 60 patients with gastrointestinal tumors who received IPHC in our hospital were divided into control group (low dose 0.2 渭 g / kg,n=30) and observation group (high dose 0.5 渭 g / kg,n=30). The changes of vital signs and anesthetic effect between the two groups were compared and analyzed. Results: the excellent and good rate of anesthesia in the observation group was 100%, which was significantly higher than that in the control group (90.00%). The vital signs of the patients during operation were more stable and recovered faster after operation. There was significant difference between the two groups (P 0.05). Conclusion: different doses of dexmetomide can be used in patients with gastrointestinal tumors during perioperative period of IPHC, and good anesthesia and sedation effect can be obtained, and the effect of high dose is better.
【作者单位】： 甘肃省武威医学科学院肿瘤医院麻醉科;
【分类号】：R614;R735
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本文编号：2513259