Hp感染对代谢综合征患者血压、空腹血糖和高敏C反应蛋白的影响及意义

发布时间：2017-12-31 21:12

本文关键词：Hp感染对代谢综合征患者血压、空腹血糖和高敏C反应蛋白的影响及意义　出处：《山东医药》2016年08期 　论文类型：期刊论文

【摘要】：目的探讨幽门螺杆菌(Hp)感染对代谢综合征(MS)患者血压(SBP、DBP)、空腹血糖(FPG)、高敏C反应蛋白(hs-CRP)的影响及意义。方法选择MS患者1 600例,根据13C-尿素呼气试验结果分为Hp阳性组1 091例、Hp阴性组509例。比较两组SBP、DBP及血清FPG、hs-CRP水平,并分析其与Hp感染状态的关系。结果 Hp阳性组SBP为(132.52±24.33)mm Hg、DBP为(81.34±12.91)mm Hg,Hp阴性组分别为(130.22±23.13)、(79.98±11.45)mm Hg,两组比较P均0.05。Hp阳性组血清FPG为(7.68±3.62)mmol/L、hs-CRP为(3.48±0.26)mg/d L,Hp阴性组分别为(5.84±2.11)mmol/L、(1.92±0.43)mg/d L,两组比较P均0.05。相关分析发现,Hp感染状态与MS患者血压无相关性,与血清FPG、hs-CRP水平均呈正相关(r分别为0.524、0.788,P均0.05)。结论Hp感染可加重MS患者的代谢紊乱状态;对Hp阳性的MS患者应尽早行Hp根除治疗。
[Abstract]:Objective to investigate the effect of Helicobacter pylori (HP) infection on the blood pressure of patients with metabolic syndrome (MS), SBP and DBP, fasting blood glucose (FPG). Methods 1 600 patients with MS were divided into HP positive group (1 091 cases) according to 13C- urea breath test. The serum levels of SBP, DBP and serum FPGG hs-CRP were compared in 509 cases of HP negative group. Results the SBP of HP positive group was 132.52 卤24.33 mm Hg, and that of HP positive group was 81.34 卤12.91 mm Hg. The HP negative group was 79.98 卤11.45 mm Hg. The serum FPG in both groups was 7.68 卤3.62 mmol / L and 3.48 卤0.26 mg / d / d, respectively. The HP negative group was 5.84 卤2.11 mmol / L, 1.92 卤0.43 mg / d L, respectively (P 0.05). There was no correlation between HP infection status and blood pressure in MS patients, and there was a positive correlation between HP infection status and serum FPGN hs-CRP level (r = 0.524 卤0.788, respectively). Conclusion HP infection can aggravate the metabolic disorder in MS patients. Hp-positive MS patients should be treated with HP eradication as soon as possible.
【作者单位】：江苏省太湖干部疗养院;
【分类号】：R589
【正文快照】： 代谢综合征(MS)是一组复杂的代谢紊乱症候群。以往研究认为,幽门螺杆菌(Hp)感染可干扰糖脂代谢、介导炎症反应等,增加罹患糖尿病的风险[1~4]。近年研究发现,MS的发生、发展可能与Hp感染有关。有学者认为,慢性Hp感染是高血压患病的危险因素之一,但Hp感染与高血压关系的报道较少

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