循环运动训练对2型糖尿病妇女心肺适能及血流介导的血管舒张功能的影响

发布时间：2018-02-20 15:09

本文关键词： 循环运动训练型糖尿病血流介导的血管舒张最大摄氧量炎症　出处：《中国康复医学杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的:研究循环运动训练对2型糖尿病妇女心肺适能及血流介导的血管舒张功能(FMD)的影响,探讨循环运动训练对2型糖尿病患者心血管功能的影响及机制。方法:8例2型糖尿病妇女进行12周的循环运动训练,采用超声技术测试受试者循环运动训练前、后的血流介导血管舒张功能,采用Astrand-Ryhnuiy列线图法间接推测受试者最大摄氧量,并对血清脂代谢指标和血清白细胞介素-6(IL-6),C-反应蛋白(CRP)的水平进行检测。同时将8例同年龄段、健康非糖尿病妇女作为正常对照组。结果:经过12周循环运动训练后,糖尿病妇女的体脂率(30.42%±1.80%vs 28.10%±1.50%)、糖化血红蛋白(7.31%±0.70%vs 6.88%±0.76%)等显著下降(P0.05),同时,FMD(7.32%±1.29%vs 9.37%±0.89%)显著增加(P0.05),最大摄氧量([1.73±0.22)L/min vs(2.10±0.32)L/min]显著增加(P0.05),IL-6([0.78±0.13)ng/L vs(0.40±0.15)ng/L]、CRP([9.97±0.96)mg/L vs(7.32±1.02)mg/L]水平显著降低(P0.05)。所有受试者的FMD增加的程度与最大摄氧量增加程度、血清IL-6和CRP降低的程度呈显著正相关。结论:循环运动训练能改善糖尿病妇女血流介导的血管舒张功能,循环运动训练改善心血管功能的机制与心肺适能的提高及炎症水平的降低有关。
[Abstract]:Objective: to study the effects of circulatory exercise training on cardiopulmonary fitness and blood flow mediated vasodilation function (FMDs) in type 2 diabetic women. To explore the effect and mechanism of circulatory exercise training on cardiovascular function in patients with type 2 diabetes mellitus (T2DM) methods eight women with type 2 diabetes underwent 12 weeks of circulatory exercise training. The vasodilation function was mediated by blood flow. The maximal oxygen uptake was estimated indirectly by Astrand-Ryhnuiy method, and the serum lipid metabolism index and serum interleukin-6 (IL-6) -reactive protein (IL-6) -reactive protein (IL-6) level were measured in 8 patients of the same age group. Healthy non-diabetic women served as normal control group. Results: after 12 weeks of cyclic exercise training, The body fat rate of diabetic women was 30.42% 卤1.80% vs 28.10% 卤1.50%, the saccharified hemoglobin 7.31% 卤0.70% vs 6.88% 卤0.76g / L significantly decreased P0.05, while FMD7.32% 卤1.29 vs 9.37% 卤0.89 increased P0.055.The maximal oxygen uptake ([1.73 卤0.22 vs(2.10 卤0.32hl / min] increased significantly ([0.78 卤0.13ngL vs(0.40 卤0.15ngL] CRP (9.97 卤0.96mgL 卤vs(7.32 1.02mg / L). The degree of increase in oxygen uptake, Conclusion: circulatory exercise training can improve blood flow mediated vasodilation function in diabetic women. The mechanism of circulatory exercise training in improving cardiovascular function is related to the increase of cardiopulmonary fitness and the decrease of inflammation level.
【作者单位】：石家庄学院体育学院运动人体科学实验中心;河北医科大学第二医院内分泌科;
【基金】：石家庄学院科研平台启动基金项目(xJpT005)
【分类号】：R493;R587.1

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