云南地区中青年男性养路工人骨质疏松危险因素筛查

发布时间：2018-03-04 21:29

本文选题：云南地区　切入点：中青年男性　出处：《昆明医科大学》2016年硕士论文　论文类型：学位论文

【摘要】：[目的]：1.测定云南地区养路工人跟骨超声参数,了解云南省中青年男性养路工人骨量情况。2.调查云南地区养路工人人口学特征及其生活方式,了解跟骨超声参数的危险因素,降低其骨质疏松症的风险,提高工人生活质量。[方法]：1.云南地区包括16个州／市,对应于每个州/市,云南省公路局的公路管理总段共16个。通过整群随机抽样方法从每个公路管理总段中抽取2个公路管理段(一共32个),调查所抽到的公路管理段的全部中青年男性养路工人,共548例,年龄20-64岁。2.利用Hologic公司生产的Sahara超声骨密度仪测量跟骨骨密度(bone mineral density, BMD)、定量超声指数(Quantitative Ultrasound Index, QUI)及T值。计算平均的BMD、QUI、T值。以10岁为一个年龄组将其分为4组,分别计算每一组的BMD、QUI及T值,了解其峰值骨量及出现的年龄,并计算异常骨量的发生率。3.调查养路工人的一般人口学特征及生活习惯等,分析该人群的骨质疏松的风险因素。[结果]：1.云南地区中青年男性养路工人体重指数高(平均BMI:24.9kg/m2);日照时间长(5.61小时/天)；少数民族比例高(29.93%)；有其他疾病的比例大(57.3%),吸烟比例大(60.4%)；饮酒比例大(77.4%)。2.云南地区中青年男性养路工人的平均BMD为0.497g/cm2, QUI为90.104,平均T值为-0.838。其骨密度、QUI及T值的峰值都出现在20-29岁组,分别为：0.560g/cm2、100.641、-0.350。正常骨量302人(55.11%),骨量异常346人(44.89%)。3.单因素分析显示：年龄、吸烟量、吸烟时间与跟骨BMD、QUI呈负相关,少数民族工人的跟骨BMD和QUI高于汉族工人。合并3种及以上的疾病比没有其他疾病的工人的跟骨BMD、QUI值低。4.多重直线回归分析显示年龄、吸烟量、民族是骨质疏松BMD和QUI的风险因素。[结论]：1.云南地区中青年男性养路工人的跟骨骨密度和QUI峰值出现在20-29岁组,分别为0.560g/cm2、100.641,随着年龄增加跟骨BMD和QUI值降低。跟骨骨量异常比例高(44.89%)。2.年龄、吸烟量、汉族是云南省中青年男性养路工人骨质疏松症的独立危险因素。
[Abstract]:[objective] to determine the ultrasonic parameters of calcaneal bone of road maintenance workers in Yunnan, and to understand the bone mass of young and middle-aged male road workers in Yunnan Province. 2. To investigate the demographic characteristics and lifestyle of road maintenance workers in Yunnan, and to understand the risk factors of ultrasonic parameters of calcaneus. Reduce the risk of osteoporosis, improve the quality of life of workers. [methods] Yunnan region includes 16 states / cities, corresponding to each state / city, The total section of highway management of Yunnan Provincial Highway Bureau is 16. Two sections of highway management were selected from each section by cluster random sampling (32 pieces in total, all middle and young male road maintenance workers in the selected section of highway management were investigated. A total of 548 cases, aged 20-64 years, were enrolled in this study. Bone mineral density (BMD), quantitative Ultrasound Index (QUI) and T value of calcaneal bone mineral density were measured by using Sahara ultrasonic bone densitometer produced by Hologic Company. The mean value of BMD-QUIU T was calculated. The BMD-QUI and T values of each group were calculated respectively to understand the peak bone mass and the age of occurrence, and the incidence of abnormal bone mass was calculated .3.The general demographic characteristics and living habits of road maintenance workers were investigated. Analysis of the risk factors of osteoporosis in this population. [results] 1. Middle and young male road maintenance workers in Yunnan have a high BMI (average BMI: 24.9 kg / m2; long sunshine time of 5.61 hours / day); a high proportion of ethnic minorities (29.93%); and a large proportion of other diseases (57.3%). The average BMD, QUI and T value of middle and young male road maintenance workers in Yunnan area were 0.497g / cm ~ 2, 90.104 and -0.838 respectively. The peak values of QUI and T value of bone mineral density (QUI) and T value appeared in 20-29 years old group. The normal bone mass of 302 people was 55.111.The bone mass of 346 people with abnormal bone mass was 44.890.3.The univariate analysis showed that age, smoking quantity and smoking time were negatively correlated with calcaneal BMD-QUI. The calcaneal BMD and QUI of minority workers were higher than that of Han nationality workers. Nationality is the risk factor for BMD and QUI of osteoporosis. [conclusion] 1. Bone mineral density of calcaneus and peak value of QUI in middle and young male road workers in Yunnan area were found in 20-29 years old group. The values of BMD and QUI of calcaneal bone decreased with the increase of age. The ratio of abnormal calcaneal bone mass was 44.89. 2. Age, smoking volume and Han nationality were independent risk factors of osteoporosis among young and middle-aged male road workers in Yunnan Province.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R580

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