粉尘螨过敏患者Der f 1和Der f 2特异性IgE的检测分析

发布时间：2018-04-05 07:51

本文选题：粉尘螨　切入点：过敏原　出处：《厦门大学学报(自然科学版)》2017年01期

【摘要】：为了解粉尘螨(Dermatophagoides farinae)过敏患者对粉尘螨单组分过敏原Der f 1和Der f 2特异性IgE的水平情况,收集了80例疑似尘螨过敏患者样本,对ImmunoCAP过敏原检测系统和浙江大学迪迅粉尘螨检测试剂盒检测的粉尘螨特异性IgE阳性样本,进一步检测其粉尘螨单组分过敏原Der f 1和Der f 2特异性IgE水平.80例样本中2种方法检测粉尘螨均为阳性的有65例,阳性率为81.3%.65例阳性样本中,Der f 1阳性率为87.7%,Der f 2阳性率为90.8%,二者至少一个为阳性的达96.99%,Der f 2特异性IgE水平显著高于Der f 1.儿童的粉尘螨及其2种单组分过敏原Der f 1和Der f 2特异性IgE水平显著高于成人.综上,Der f 1和Der f 2这2种组分过敏原在我国粉尘螨患者中占据了主导地位,两者特异性IgE水平存在显著差异,后者高于前者,且儿童的敏感性显著高于成人.
[Abstract]:In order to understand the specific IgE levels of Dermatophagoides farinaeus allergen Der f 1 and Der f 2 in patients with Dermatophagoides farinae, 80 samples of suspected dust mite allergies were collected.The specific IgE positive samples of Dermatophagoides farinae detected by ImmunoCAP allergen detection system and Dishon Dermatophagoides farinae detection kit of Zhejiang University were analyzed.The specific IgE levels of Der f1 and Der f 2 were further detected in 65 of the 80 samples of Dermatophagoides farinae.The positive rate of Der f1 was 87.7% and the positive rate of Der f2 was 90.8. The specific IgE level of Der f2 was significantly higher than that of Der f1 in at least one of them.The specific IgE levels of Der f 1 and Der f 2 were significantly higher in children than in adults.The allergens of Der f 1 and Der f 2 played a dominant role in the patients with Dermatophagoides farinae in China. There was a significant difference in the specific IgE levels between them. The latter was higher than the former, and the sensitivity of children was significantly higher than that of adults.
【作者单位】：浙江大学医学院附属邵逸夫医院;
【基金】：浙江省重大(重点)国际科技合作项目(2009C14029)
【分类号】：R593.1

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