山西省太原市部分城区成年人群骨密度相关影响因素的研究

发布时间：2018-04-08 16:02

本文选题：骨质疏松症　切入点：骨密度　出处：《山西医科大学》2017年硕士论文

【摘要】：目的:通过测量山西省太原市部分城区居民身高、体重、腰椎骨密度(bone mineral density,BMD),调查其生活方式、既往史和家族史,探讨影响太原市部分城区成年人群BMD的相关影响因素,并了解太原市部分城区成年人群骨质疏松症患病现状,为太原市部分城区成年人群骨质疏松症的防治提供简易、廉价、科学的临床参考依据。方法:从山西省太原市部分城区常住居民中,随机抽取1393名作为调查对象,根据调查资料的完整性及纳入标准,最终纳入529名作为研究对象。研究内容包括:(1)问卷调查:基本资料、既往脆性骨折史、家族骨质疏松史、家族脆性骨折史、吸烟史、饮酒史、饮牛奶情况、日晒及运动情况;(2)体格检查:身高、体重,计算体重指数;(3)BMD测量:使用双能X线BMD测量仪测定腰椎BMD。用SPSS17.0统计软件对数据进行统计学处理:计量资料用(?)±s表示;计数资料用百分比或率表示;所测量数据进行正态分布检验,检验结果显示所获得的数据呈正态分布;多组间比较采用单因素方差分析,组间两两比较采用LSD-t检验;计数资料率或构成比的比较采用X~2检验或fisher精确概率法;多因素分析采用logistic回归分析。P0.05表示差异具有统计学意义。结果:1.在男性和女性人群中,腰椎BMD在青年组、中年组和老年组三组间两两比较均具有统计学差异(P0.05),且腰椎BMD随年龄的增长而减低。在男性和女性人群中,骨质疏松症患病率在青年组、中年组和老年组三组间两两比较具有统计学差异(P0.05),骨质疏松症患病率随年龄的增长而升高,且老年女性的骨质疏松症患病率比老年男性高。2.在不同年龄组,腰椎BMD在体重正常组、超重组和肥胖组三组间两两比较具有统计学差异(P0.05),腰椎BMD随BMI的降低而减低。在老年组,骨质疏松症患病率在体重正常组、超重组和肥胖组三组间两两比较具有统计学差异(P0.05),且骨质疏松症患病率随BMI的降低而升高。在青年组和中年组的各BMI组间,骨质疏松症患病率的比较无统计学差异。3.在女性人群中,绝经组与未绝经组和围绝经组比较均具有统计学差异(P0.05),未绝经组与围绝经组比较无统计学差异,且绝经组的腰椎BMD低于未绝经组和围绝经组。骨质疏松症患病率在未绝经组、围绝经组和绝经组三组间两两比较具有统计学差异(P0.05),且随绝经年限的延长,骨质疏松症患病率升高。4.家族骨质疏松症史和既往脆性骨折史是骨质疏松的危险因素;有家族骨质疏松症史和既往脆性骨折史人群的骨质疏松症患病率偏高。5.吸烟、饮酒是骨质疏松的危险因素,每天饮用牛奶、坚持运动、增加日晒时间是骨质疏松的保护因素;不良生活方式人群的骨质疏松症患病率偏高。结论:1.太原市部分城区居民骨质疏松症患病率高于全国平均水平。2.腰椎BMD随年龄的增长而减低,骨质疏松症患病率随年龄的增长而升高。3.腰椎BMD随BMI的降低而减低,老年人群骨质疏松症患病率随BMI的降低而升高。4.绝经后女性的腰椎BMD低于未绝经和围绝经女性,骨质疏松症患病率随绝经年限的延长而升高。5.脆性骨折史、家族骨质疏松症史、吸烟、饮酒是骨质疏松的危险因素,使骨质疏松症患病率升高。
[Abstract]:Objective: to measure the part of the city residents in Shanxi city of Taiyuan Province, height, weight, bone mineral density (bone mineral, density, BMD), to investigate the way of life, past history and family history, to explore the related factors affecting part of the city of Taiyuan city adults BMD, and understand the part of the city of Taiyuan city adults osteoporosis prevalence as part of the city of Taiyuan City, prevention and treatment of osteoporosis in adults provides a simple, inexpensive, clinical scientific basis. Methods: from the part of the city of Shanxi province Taiyuan city residents, 1393 randomly selected as the research object, according to the integrity of the survey data and the inclusion criteria, ultimately included 529 research as the research object. The contents include: (1) questionnaire: basic information, history of brittle fracture history, family history of osteoporosis, the brittle fracture of family history, smoking history, drinking history, drinking milk, and the sun sports Condition; (2) physical examination: height, weight, body mass index (BMD; 3) measurement: using dual energy statistical data using SPSS17.0 statistical software for determination of lumbar BMD. X-ray BMD measuring instrument: measurement data with (?) + s; count data show rate percentage or the measured data; normal distribution test, test results show that the normal distribution of data obtained; multiple groups were analyzed using single factor analysis of variance between the 22 groups were compared with LSD-t test; count data rate or ratio compared with X~2 test or Fisher exact probability method; multivariate analysis using logistic regression analysis with statistical.P0.05 results: 1.. Significant differences in men and women, lumbar BMD in the youth group, middle age group and elderly group three between the 22 groups were statistically different (P0.05), and lumbar BMD age growth decreased. In men and women In the crowd, the prevalence rate of osteoporosis in young group, middle age group and elderly group three comparison between the 22 groups had statistical differences (P0.05), the prevalence of osteoporosis increases with age, and older women the prevalence of osteoporosis in elderly men with high.2. ratio in different age group, lumbar BMD in weight normal group, overweight group and obesity group three between the 22 groups was statistically difference (P0.05), lumbar BMD decreases with the decrease of BMI. In the older age group, the prevalence rate of osteoporosis in the normal weight group, overweight and obese group three between the 22 groups was statistically difference (P0.05), and osteoporosis with the prevalence of BMI was increased. In the young and middle-aged group of the BMI group, the prevalence rate of osteoporosis in.3. had no significant difference in women, menopause group compared with premenopausal group and postmenopausal group were statistically significant (P0 .05), premenopausal group and postmenopausal group were no significant difference, and menopause group lumbar BMD was lower than that of premenopausal group and postmenopausal group. The prevalence rate of osteoporosis in premenopausal group and postmenopausal group and postmenopausal group three between the 22 groups was statistically difference (P0.05), and with the prolonged duration of menopause the prevalence of osteoporosis and osteoporosis increased.4. family history and past history of fragility fractures are risk factors for osteoporosis; with a prevalence of osteoporosis.5. high smoking family history and past history of fragility fractures crowd of osteoporosis, drinking is a risk factor for osteoporosis, drink milk every day, exercise, increase the sun time is a protective factor for osteoporosis; people of high prevalence of unhealthy lifestyle osteoporosis. Conclusion: osteoporosis is part of the city residents of Taiyuan city in 1. prevalence rate is higher than the national average of.2. lumbar vertebra with BMD The growth of the age and reduce the prevalence of osteoporosis increases with age of.3. lumbar BMD decreases with the decrease of BMI, the elderly population prevalence of osteoporosis increased with the decrease of BMI and.4. in postmenopausal women with lumbar BMD was lower than that of premenopausal and postmenopausal women, the prevalence of osteoporosis with prolonged duration of menopause the increased.5. brittle fracture history, smoking, family history of osteoporosis, and drinking are the risk factors of osteoporosis, the prevalence of osteoporosis increases.

【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R580

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