中西医结合治疗多囊卵巢综合征合并胰岛素抵抗肥胖患者临床疗效观察

发布时间：2018-04-13 13:09

本文选题：多囊卵巢综合征 + 胰岛素抵抗　；参考：《中国中医基础医学杂志》2017年08期

【摘要】：目的:观察探讨名中医亓鲁光教授中西医结合治疗多囊卵巢综合征(PCOS)合并胰岛素抵抗(IR)肥胖患者,与常规西药比较并观察疗效。方法:PCOS合并IR肥胖患者60例,按随机数字表法分为西药组和中西医组,2组患者均服用盐酸二甲双胍片,中西医组加服亓鲁光教授经验方消脂汤,治疗随访3个月观察疗效、孕激素水平、空腹血糖(FBG)及餐后2h血糖(2hPG)水平、体质量指数(BMI)、受孕情况及不良反应。结果:中西医组总有效率93.10%,显著优于西药组的85.71%;治疗后血清卵泡刺激素(FSH)、黄体生成激素(LH)、LH/FSH比值、总睾酮(T)、FBG、2hPG、BMI较治疗前显著下降,其中中西医组治疗后LH、LH/FSH、BMI和2hPG变化较西药组明显;治疗及随访期间西药组和中西医组各有2例、6例患者受孕,2组患者均未有不良反应报告。结论:亓鲁光教授中西医结合治疗多囊卵巢综合征合并胰岛素抵抗肥胖疗效可靠,值得临床推广运用。
[Abstract]:Objective: to observe the effect of traditional Chinese medicine (Qi Luguang) and traditional Chinese medicine (TCM) combined with western medicine on the treatment of polycystic ovary syndrome (PCOS) with insulin resistance (IRR) obesity patients.Methods Sixty patients with weight PCOS combined with IR were randomly divided into western medicine group and traditional Chinese and western medicine group. The patients in both groups were treated with metformin hydrochloride tablets, and those in traditional Chinese and western medicine group were treated with Qi Luguang experience prescription Xiaozhi decoction, and the curative effect was observed after 3 months follow-up.The levels of progesterone, fasting blood glucose (FBG) and 2 h postprandial blood glucose (2 h), body mass index (BMI), pregnancy status and adverse reactions were observed.During the course of treatment and follow-up, there were 2 cases of pregnancy in the western medicine group and 2 cases in the western medicine group and 2 cases in the western medicine group respectively. No adverse reactions were reported in the two groups.Conclusion: professor Qi Luguang combined with traditional Chinese and Western medicine in the treatment of polycystic ovary syndrome with insulin resistance obesity is effective and worthy of clinical application.
【作者单位】：成都市玉林社区卫生服务中心;南方医科大学中医药学院;成都中医药大学附属医院;
【分类号】：R711.75

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