终末糖基化产物在糖尿病勃起功能研究中的进展
发布时间:2018-05-03 14:51
本文选题:终末糖基化产物 + 糖尿病 ; 参考:《中国老年学杂志》2017年20期
【摘要】:正勃起功能障碍(ED)是指在有性交意愿的情况下阴茎持续至少3个月不能达到和(或)维持充分的勃起状态而获得满意的性生活~([1])。DM中ED患者为正常人群的3倍,且ED发生较正常人群早10~15年~([2~4])。DM阴茎组织中终末糖基化产物(AGEs)含量较正常人明显增多~([5]),应用AGEs抑制剂能改善DM大鼠勃起功能~([6])。本文对AGEs在DMED的发生、发展中
[Abstract]:Erectile dysfunction (EDD) is three times the number of patients with Ed who are not able to achieve and / or maintain a full erectile state for at least 3 months if they have sexual intercourse ([1] .DM). In addition, Ed occurred 10 ~ 15 years earlier than that in normal subjects ([2] 4). The end glycosylation products (ages) in the penile tissue of DM were significantly higher than those in normal controls ([5]). The application of AGEs inhibitor could improve erectile function in DM rats ([6]). This paper deals with the occurrence and development of AGEs in DMED.
【作者单位】: 佳木斯大学附属第一医院;佳木斯大学基础医学院;
【基金】:黑龙江省自然科学基金(No.H2015073) 佳木斯大学重点项目(No.Sz2013-005)
【分类号】:R587.2;R698
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