男性雄性激素缺乏对生命质量影响的初步分析

发布时间：2018-05-11 00:03

本文选题：男性激素 + 生命质量　；参考：《中国现代医学杂志》2017年24期

【摘要】：目的探究雄性激素缺乏对男性生命质量的影响。方法分层整群抽样的方法抽取遵义市1 166例成年男性作为调查对象,每位调查对象完成基本信息、生命质量量表(SF-36)填写,并完成身高体重测量、血清激素水平检测。排除有疾病史的对象428例,剩余738例纳入分析。对生命质量生理领域、心理领域及总分的影响因素采用多元线性回归进行筛选。筛选出的影响因素进行组间方差分析比较。结果多元线性回归结果显示,纳入观察的4个雄性激素指标中,睾酮分泌指数与心理领域评分独立关联(b=10.880,P=0.033)。此外,年龄、结扎及文化水平分别与生理领域评分独立关联;结扎、体质指数及婚姻状态分别与心理领域评分独立关联;年龄、结扎、文化水平及体质指数分别与生命质量总分独立关联(均P0.05)。方差分析结果显示睾酮分泌指数在生理职能、社会功能及情感职能维度有差异,且激素缺乏组的评分低于正常组。结论较好的睾酮分泌能力可能是男性生命质量的保护因素;此外较高的体质指数及文化水平也可能是生命质量的保护因素,而高龄、结扎史则可能是男性生命质量的危险因素。
[Abstract]:Objective to investigate the effect of male hormone deficiency on male quality of life. Methods 1 166 adult males in Zunyi were selected by stratified cluster sampling. Each of them completed basic information, quality of life scale (SF-36), height and weight measurement, and serum hormone level. 428 patients with history of disease were excluded and the remaining 738 cases were included in the analysis. Multiple linear regression was used to screen the influencing factors of quality of life physiology field, psychological field and total score. The selected factors were compared by ANOVA. Results the results of multiple linear regression showed that the testosterone secretion index and the score of psychological field were independently correlated with the four indexes of androgen. In addition, age, ligation and cultural level were independently correlated with the score of physiological field; ligation, BMI and marital status were independently correlated with score of psychological field; age, ligation, ligation, The educational level and body mass index were independently correlated with the total score of quality of life (all P 0.05). The results of variance analysis showed that testosterone secretion index was different in physiological function, social function and affective function, and the score of hormone deficiency group was lower than that of normal group. Conclusion the better testosterone secretion ability may be the protective factor of male life quality, and the higher body mass index and education level may also be the protection factor of life quality, while the senior age and the history of ligation may be the risk factors of male life quality.
【作者单位】：遵义医学院公共卫生学院;华中科技大学同济医学院计划生育研究所;
【基金】：国家“十二五”基金(No:2012BAI32B03)
【分类号】：R58

【相似文献】