糖尿病肾病与维吾尔族T2DM患者其他糖尿病并发症的相关性分析

发布时间：2018-05-23 11:15

本文选题：型糖尿病 + 糖尿病肾病　；参考：《中国现代医学杂志》2017年11期

【摘要】：目的探讨维吾尔族2型糖尿病(T2DM)患者糖尿病肾病与其他糖尿病并发症之间的相关性。方法选取2015年3月-2016年3月新疆乌鲁木齐市某三甲医院确诊的维吾尔族2型糖尿病患者558例,测量2型糖尿病患者各临床及生化指标并记录其糖尿病并发症,通过χ2检验和多因素二分类logistic回归分析方法比较糖尿病肾病和其他糖尿病并发症的相关性。结果 558例维吾尔族2型糖尿病患者当中,155例患有糖尿病肾病,占总人数的27.8%;403例无糖尿病肾病,占总人数的72.2%;高血压患病数最高335例,占总人数的60.0%;脑血管病患病数最低105例,占总人数的18.8%。通过χ~2检验发现,糖尿病肾病与糖尿病合并冠心病、高血压、视网膜病变及周围神经病变的差异有统计学意义(P0.05);糖尿病肾病与糖尿病合并脂肪肝、脑血管病及周围血管病的差异无统计学意义(P0.05)。通过多因素二分类logistic回归分析发现,维吾尔族2型糖尿病患者合并冠心病、高血压、视网膜病变、周围神经病变及脑血管病变为发生糖尿病肾病的危险因素,OR1。结论糖尿病肾病与糖尿病合并冠心病、高血压、视网膜病变及周围神经病变可作为相互的危险因素。
[Abstract]:Objective to investigate the correlation between diabetic nephropathy and other diabetic complications in Uygur patients with type 2 diabetes mellitus (T2DM). Methods from March 2015 to March 2016, 558 Uygur patients with type 2 diabetes were selected from a third Class A Hospital in Urumqi, Xinjiang. The clinical and biochemical indexes of type 2 diabetes were measured and their diabetic complications were recorded. The correlation between diabetic nephropathy and other diabetic complications was compared by 蠂 2 test and multivariate logistic regression analysis. Results among the 558 Uygur patients with type 2 diabetes, 155 had diabetic nephropathy, accounting for 27.8% of the total number of diabetic nephropathy, accounting for 72.2% of the total number of diabetic nephropathy, 335 cases of hypertension accounted for 60.0% of the total, and 105 cases of cerebrovascular disease were the lowest. 18.8% of the total. The results of 蠂 2 test showed that there were significant differences between diabetic nephropathy and diabetic complicated with coronary heart disease, hypertension, retinopathy and peripheral neuropathy (P 0.05), diabetic nephropathy and diabetes mellitus complicated with fatty liver. There was no significant difference between cerebrovascular disease and peripheral vascular disease (P 0.05). Logistic regression analysis showed that Uygur patients with type 2 diabetes complicated with coronary heart disease, hypertension, retinopathy, peripheral neuropathy and cerebrovascular disease. Conclusion Diabetic nephropathy and diabetic complicated with coronary heart disease, hypertension, retinopathy and peripheral neuropathy may be risk factors for each other.
【作者单位】：新疆医科大学公共卫生学院劳动卫生与环境卫生学教研室;
【基金】：国家自然科学基金(No:81360127)
【分类号】：R587.2

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