有结节性红斑表现的强直性脊柱炎10例并文献复习

发布时间：2018-06-03 07:31

本文选题：结节性红斑 + 强直性脊柱炎　；参考：《中国皮肤性病学杂志》2017年07期

【摘要】：目的提高结节性红斑(EN)与强直性脊柱炎(AS)相关性的关注。方法收集10例伴有EN表现的AS患者的临床资料,对其临床表现、实验室及辅助检查结果进行分析。结果 10例患者中,男性4例,女性6例,平均年龄(35±8)岁,病程6个月~30年。红斑部位多见于小腿伸侧,伴或不伴有外周关节炎/关节痛,受累关节主要为下肢大关节;6例有腰背痛,1例有趾炎,5例有足跟痛,3例有口腔溃疡,5例HLA-B27阳性,3例ESR和5例CRP水平升高,骶髂关节X片或CT双侧II级9例,骶髂关节X片单侧III级1例。结论对有EN表现,排除感染、结缔组织病等常见病因后,当患者表现有一种或一种以上脊柱关节炎(SpA)的临床表现或HLA-B27阳性,应筛查SpA相关检查,警惕隐匿性AS存在。
[Abstract]:Objective to improve the relationship between ENN and ASA in ankylosing spondylitis. Methods the clinical data of 10 patients with en were collected and the clinical manifestations, laboratory and auxiliary findings were analyzed. Results among the 10 patients, 4 were male and 6 were female, with an average age of 35 卤8 years. The course of disease ranged from 6 months to 30 years. Erythema was more common in the extended leg with or without peripheral arthritis / arthralgia. The main involved joints were 6 cases of lower extremity major joint with low back pain, 1 case with phalanitis, 5 cases with heel pain, 3 cases with oral ulcers, 5 cases with HLA-B27 positive, 3 cases with ESR and 5 cases with elevated CRP level. Sacroiliac joint X film or CT was bilateral grade II in 9 cases. One case of III grade on X-ray of sacroiliac joint. Conclusion after the common etiology of en, excluding infection, connective tissue disease and so on, when the patient has one or more kinds of spinal arthritis (Spa) clinical manifestation or HLA-B27 positive, we should screen the SpA correlation examination and be alert to the existence of concealed as. [WT5HZ] [WT5 "HZ] [WT5BZ] [WT5" BZ] [WT5 "BZ]
【作者单位】：兰州大学第二临床医学院;兰州大学第二医院风湿免疫科;
【基金】：甘肃省卫生行业科研计划管理项目(GWGL2014-47) 国家自然科学基金(81560267) 兰州大学第二医院院内课题(ynbskyjj2015-1-14)
【分类号】：R593.23

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