实时三维超声心动图及二维斑点追踪技术评价SLE合并PAH患者双心室收缩功能的研究

发布时间：2018-06-05 07:15

本文选题：超声心动描记术 + 系统性红斑狼疮　；参考：《四川大学学报(医学版)》2017年04期

【摘要】：目的使用实时三维超声心动图技术(RT-3DE)和二维斑点追踪技术(2D-STI)评估系统性红斑狼疮(SLE)所致的肺动脉高压(PAH)对双心室收缩功能的影响。方法将研究对象按有无PAH及严重程度分为无(NPAH)、轻(LPAH)、中(MPAH)及重度PAH(SPAH)组,各为23例,19例,18例,12例。RT-3DE获取双心室射血分数(LVEF/RVEF),通过2D-STI计算左心室前壁(ANT)、室间隔(SEP)、侧壁(LAT)及下壁(INF)心肌纵向应变(LS)平均值(LSA)及圆周应变(CS)平均值(CSA),比较各组间的差异。结果仅SPAH组LVEF值降至正常水平以下;而LS随PAH增加而降低,ANT及SEP的LSA降低明显,而INF及LAT变化较不明显;CS则先增加后降低,SEP、ANT及INF的CSA变化比较明显。结论 SLE所致的PAH对双心室收缩功能均有影响。
[Abstract]:Objective to evaluate the effects of pulmonary hypertension (PAH) induced by systemic lupus erythematosus (SLEs) by real-time three-dimensional echocardiography (RT-3DE) and two-dimensional speckle tracing (2D-STI) on the systolic function of the two ventricles. Methods according to the degree and severity of PAH, the subjects were divided into three groups: NPAH, LPAH, MPAH and SPAH. The mean values of LVEF / RVEFV were calculated by 2D-STI in left ventricular anterior wall, septal septum, lateral wall (LATA) and inferior wall (INFN), and the mean values of LSAs and CSCSSAs were compared between the two groups, and the difference between the two groups was compared. The results showed that the mean value of LVEF / RVEFV was calculated by 2D-STI in the left ventricular anterior wall, the septum of the left ventricular septum, the LSs of the left ventricular septum and the inferior wall of the left ventricular wall, and the mean values of the longitudinal strain and the LSs of the inferior wall were compared. Results the LVEF value of SPAH group decreased below the normal level, while the LSA of ANT and SEP decreased significantly with the increase of PAH, while the changes of INF and LAT were significantly lower than those of CS. The changes of CSA in SPAH group were higher than those in SPAH group, and then the changes of CSA in SPAH group were higher than those in SPAH group. Conclusion PAH induced by SLE has an effect on biventricular systolic function.
【作者单位】：四川大学华西医院心血管内科;四川大学华西医院上锦分院心血管内科;
【分类号】：R544.1;R593.241

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