裸燕麦对2型糖尿病合并高血压患者血压的影响研究

发布时间：2018-06-06 12:09

  本文选题：糖尿病 + 型　； 参考：《中国全科医学》2016年05期

【摘要】：背景医学营养疗法对2型糖尿病合并高血压患者的疾病管理具有重要作用,但具体营养干预措施尚不统一。目的在结构化膳食控制结合健康教育的基础上,探讨全胚芽裸燕麦(NOG)对2型糖尿病合并高血压患者血压的影响。方法采用自身前后对照和多组平行对照的方法,以电话、广告途径在全国范围内招募符合纳入标准的受试者59例。采用随机数字表法将其分为A组(20例)、B组(n=20)和C组(n=19),其中A组给予结构化膳食控制及健康教育干预,B组和C组在A组的基础上分别给予50 g、100 g NOG干预,于每日早、晚两餐采用NOG粥代替能量相同的其他主食,干预28 d。干预前采集基线指标,并根据WHO标准,将所有受试者分为正常体质量〔18.5kg/m2体质指数(BMI)25.0 kg/m2〕、超重(25.0 kg/m2≤BMI30.0 kg/m2)、肥胖(BMI≥30.0 kg/m2)。于干预前及干预第28天测量所有受试者的收缩压(SBP)及舒张压(DBP)。结果 3组受试者性别、年龄、病程、空腹血糖(FBG)、餐后2 h血糖(PBG)、糖化血红蛋白、BMI比较,差异均无统计学意义(P0.05)。自身前后对照:3组受试者干预第28天SBP、DBP均分别低于同组干预前,差异有统计学意义(P0.05)。组间比较:3组受试者干预前后SBP变化值比较,差异有统计学意义(F=4.12,P=0.02);DBP变化值比较,差异无统计学意义(F=0.24,P=0.79)。双因素方差分析:3组受试者SBP干预前后变化值组间与BMI间无交互作用(P0.05),干预措施对SBP的影响有统计学意义(P0.05),BMI对SBP的影响无统计学意义(P0.05);3组受试者DBP干预前后变化值组间与BMI间无交互作用(P0.05),干预措施对DBP的影响无统计学意义(P0.05),BMI对DBP的影响无统计学意义(P0.05)。结论裸燕麦摄入及结构化膳食控制对2型糖尿病合并高血压患者均具有降血压效果,两者结合优于单纯的结构化膳食控制,且对SBP降低效果更明显。裸燕麦的降血压效果不受BMI的影响。
[Abstract]:Background Medical nutrition therapy plays an important role in disease management of patients with type 2 diabetes mellitus and hypertension, but the specific nutritional intervention measures are not uniform. Objective to investigate the effects of structured diet control and health education on blood pressure in patients with type 2 diabetes mellitus complicated with hypertension. Methods 59 subjects who met the inclusion criteria were recruited by telephone and advertisement methods. They were randomly divided into two groups: group A (n = 20) and group C (n = 19). Group A was treated with structured diet control and health education intervention. Group B and C were given 50g / 100g NOG on the basis of group A, respectively. Two late meals were treated with NOG porridge instead of other main foods with the same energy. Baseline indexes were collected before intervention, and according to WHO criteria, all subjects were divided into normal body mass index (BMI) of 18.5kg / m ~ 2 and BMI of 25.0 kg / m ~ 2, overweight of 25.0 kg/m2 鈮，

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